Effects of Heart Rate Oscillations During Meditation on Plasma Biomarkers of Alzheimer's Disease

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

94 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-01-29

Study Completion Date

2024-05-03

Brief Summary

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In the current study, we will examine how two types of concentration meditation practices affect plasma biomarkers of Alzheimer's Disease (AD). We will also examine the effects of the two types of meditation practices on emotional well-being and episodic memory. Healthy adults aged 18-35 who meet all eligibility criteria will be invited to this study. Participants will be asked to engage in one week of daily meditation practice or no-intervention control task at home. They will also be asked to visit the lab twice, once before and once after the intervention, to provide blood samples to assess plasma biomarkers of AD and to complete emotion questionnaires and a memory test.

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Detailed Description

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Conditions

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Alzheimer Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Belly-focus concentration meditation

Participants will engage in concentration meditation for 40 minutes every day for a week while recording heart rate. They will focus on the sensations around the belly.

Group Type EXPERIMENTAL

Belly-focus meditation

Intervention Type BEHAVIORAL

Participants will engage in concentration meditation for 40 minutes every day for a week. They will focus on the sensations around the belly.

Belly-focus concentration meditation with slow breathing

Participants will engage in concentration meditation and slow breathing for 40 minutes every day for a week while recording heart rate. They will focus on the sensations around the belly while breathing slowly.

Group Type EXPERIMENTAL

Belly-focus meditation with slow breathing

Intervention Type BEHAVIORAL

Participants will engage in concentration meditation and slow breathing for 40 minutes every day for a week. They will focus on the sensations around the belly while breathing slowly.

No-intervention control

Participants will rest quietly for 40 minutes every day for a week while recording heart rate.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Belly-focus meditation

Participants will engage in concentration meditation for 40 minutes every day for a week. They will focus on the sensations around the belly.

Intervention Type BEHAVIORAL

Belly-focus meditation with slow breathing

Participants will engage in concentration meditation and slow breathing for 40 minutes every day for a week. They will focus on the sensations around the belly while breathing slowly.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Fluent in English
* Aged between 18-35 years old
* Agree to provide blood samples
* Healthy adults who weigh at least 110 pounds
* Agree to devote 40 minutes daily to this study for a week

Exclusion Criteria

* Have a disorder that would affect heart rhythm or function (e.g., abnormal cardiac rhythm, dyspnea, heart disease including coronary artery disease, angina and arrhythmia)
* Regularly practicing any relaxation, meditation or yoga that involve breathing focused practices lasting for more than an hour each week

Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes