Mindfulness-based Stress Reduction and Cognitive Function in Stress and Aging

NCT ID: NCT01693874

Last Updated: 2014-07-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1/PHASE2

Total Enrollment

103 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-10-31

Study Completion Date

2014-06-30

Brief Summary

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The investigators are developing and then testing whether Mindfulness-Based Stress Reduction, a group-based instruction for increasing mindfulness, reduces anxiety and depressive symptoms and improves cognitive functioning in older adults.

Detailed Description

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Conditions

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Anxiety Disorders Depression

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Mindfulness Based Stress Reduction

All participants in this arm receive Mindfulness Based Stress Reduction (MBSR).

Group Type EXPERIMENTAL

MBSR

Intervention Type BEHAVIORAL

Mindfulness-Based Stress Reduction

control

All participants in this arm receive an attention control

Group Type ACTIVE_COMPARATOR

control (health education)

Intervention Type BEHAVIORAL

health education

Interventions

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MBSR

Mindfulness-Based Stress Reduction

Intervention Type BEHAVIORAL

control (health education)

health education

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* aged 65+
* current depressive and/or anxiety symptoms
* current depressive and/or anxiety disorder
* able to participate in behavioral study

Exclusion Criteria

* unable to participate in study
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Center for Complementary and Integrative Health (NCCIH)

NIH

Sponsor Role collaborator

University of California, San Diego

OTHER

Sponsor Role collaborator

Washington University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Eric Lenze

Professor of Psychiatry

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Eric Lenze, MD

Role: PRINCIPAL_INVESTIGATOR

Washington University School of Medicine

Julie Wetherell, PhD

Role: PRINCIPAL_INVESTIGATOR

University of California, San Diego

Locations

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University of California San Diego

San Diego, California, United States

Site Status

Washington University School of Medicine

St Louis, Missouri, United States

Site Status

Countries

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United States

References

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Kornfield SL, Nicol GE, Lenze EJ, Yingling M, Loebach Wetherell J. Mindfulness-Based Stress Reduction in Older Individuals: Who Benefits the Most? Adv Mind Body Med. 2022 Winter;36(1):4-12.

Reference Type DERIVED
PMID: 35476747 (View on PubMed)

Haddad R, Lenze EJ, Nicol G, Miller JP, Yingling M, Wetherell JL. Does patient expectancy account for the cognitive and clinical benefits of mindfulness training in older adults? Int J Geriatr Psychiatry. 2020 Jun;35(6):626-632. doi: 10.1002/gps.5279. Epub 2020 Mar 20.

Reference Type DERIVED
PMID: 32017250 (View on PubMed)

Wetherell JL, Hershey T, Hickman S, Tate SR, Dixon D, Bower ES, Lenze EJ. Mindfulness-Based Stress Reduction for Older Adults With Stress Disorders and Neurocognitive Difficulties: A Randomized Controlled Trial. J Clin Psychiatry. 2017 Jul;78(7):e734-e743. doi: 10.4088/JCP.16m10947.

Reference Type DERIVED
PMID: 28686822 (View on PubMed)

Other Identifiers

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AT007064

Identifier Type: -

Identifier Source: org_study_id

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