Effect of Prilocaine vs Bupivacaine on Hemodynamics in Spinal Anesthesia for Geriatric Patients

NCT ID: NCT06165679

Last Updated: 2025-07-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

112 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-12-20

Study Completion Date

2025-06-30

Brief Summary

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Data comparing prilocaine vs bupivacaine in equipotent doses in the elderly are lacking; therefore, the study will compare the effect of prilocaine vs bupivacaine on hemodynamics in spinal anesthesia for geriatric patients undergoing endoscopic urological surgeries

Detailed Description

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Conditions

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Hemodynamic Instability

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Prilocaine group

Group Type ACTIVE_COMPARATOR

Prilocaine

Intervention Type DRUG

The patients will receive a single injection of spinal anesthesia using prilocaine plus fentanyl

Bupivacaine GROUP

Group Type ACTIVE_COMPARATOR

Bupivacaine

Intervention Type DRUG

The patients will receive a single injection of spinal anesthesia using Bupivacaine plus fentanyl

Interventions

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Prilocaine

The patients will receive a single injection of spinal anesthesia using prilocaine plus fentanyl

Intervention Type DRUG

Bupivacaine

The patients will receive a single injection of spinal anesthesia using Bupivacaine plus fentanyl

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients aged 65 years old and above.
* Both genders.
* Patients scheduled to undergo endoscopic urological surgeries.
* ASA I and II class.

Exclusion Criteria

* Patient refusal.
* Known local anesthetic (LA) allergy.
* Bleeding disorders.
* Skin lesions or infections at site of needle insertion.
* Hypertensive patients.
* Patients candidate for transurethral resection of the prostate
* ASA III and VI class
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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AbdElKhalik Mahmoud Shaban

Lecturer of anaesthesia

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Kasr Alaini hospital

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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N-439-2023

Identifier Type: -

Identifier Source: org_study_id

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