Clinical Significance of Marginal Acute Inflammation for Stage II Colon Cancer

NCT ID: NCT06135558

Last Updated: 2023-11-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1167 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-30

Study Completion Date

2023-10-30

Brief Summary

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Marginal acute inflammation would make reporting the serosal involvement of tumors controversial. We aimed to investigate the clinical significance and explore the prognostic value of MAI for stage II localized colon cancer.

Detailed Description

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Conditions

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Inflammation Colon Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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T3

patient staged T3 without marginal acute inflammation

MAI detection

Intervention Type DIAGNOSTIC_TEST

to detect the presence of marginal acute inflammation

MAI

patient with marginal acute inflammation

MAI detection

Intervention Type DIAGNOSTIC_TEST

to detect the presence of marginal acute inflammation

T4

patient staged T4 without marginal acute inflammation

MAI detection

Intervention Type DIAGNOSTIC_TEST

to detect the presence of marginal acute inflammation

Interventions

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MAI detection

to detect the presence of marginal acute inflammation

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* (1) colon cancer patients with the preoperative staging of stage I-III who lacked distant metastasis; (2) patients who underwent radical resection, with postoperative pathology confirmed as pT3-4N0M0; and (3) complete follow-up information

Exclusion Criteria

* (1) patients who received neo-adjuvant therapy; (2) patients with multiple primary colorectal cancer; and (3) patients with a history of malignant tumors
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sun Yat-sen University

OTHER

Sponsor Role lead

Responsible Party

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Yanhong Deng

M.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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GIH-SYip32

Identifier Type: -

Identifier Source: org_study_id

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