VR Based Simulation in the Preparation of Children for MRI - MRVR

NCT ID: NCT06132854

Last Updated: 2025-05-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

288 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-11-07

Study Completion Date

2025-12-31

Brief Summary

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The goal of this randomized controlled trial is to evaluate whether a virtual reality based preparation method can efficiently decrease the proportion of children requiring general anesthesia during MRI examinations.

Participants will take part in a virtual reality environment resembling an MRI before their scheduled MRI examination.

Researchers will compare these children to usual care and a booklet based preparation method to see if less children need anesthesia for completing the MRI examination.

Detailed Description

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Study Description:

Our study investigates the efficacy of a custom-made virtual reality experience in the preparation of children for MRI examinations. We hypothesise that preparation with VR can significantly reduce the need for anesthesia in children during MRI examinations, or if anesthesia is needed less doses of anesthetics are required.

Objectives:

Primary Objective:

To evaluate whether the VR based preparation decreases the need for anesthesia and sedation during MRI examinations.

Secondary Objectives:

To evaluate whether fear, mood, anxiety, familiarity with the MRI examination of the children and willingness to take part again change as a result of the intervention.

Endpoints:

Primary Endpoint:

The need for any anesthetic or sedative medication during MRI examination.

Secondary Endpoints:

Visual analogue scales related to fear, mood and familiarity, willingness to take part in an MRI examination again.

Study Population: 288 children aged 4-18 years who are in- or outpatients at the Pediatric Center of the Semmelweis University and are scheduled for MRI examination with anesthesia will be enrolled.

Description of Sites/Facilities Enrolling Participants:

The study takes place in the two Departments of the Pediatric Centre of the Semmelweis University

Description of Study Intervention/Experimental Manipulation:

Our research will be conducted as a three arm randomized controlled trial (VR, booklet, usual care). Participants in the VR condition are immersed in a unique 360° VR experience specifically designed for this study.

Children in the booklet condition will be prepared by using an educational booklet containing colorful illustrations about the MRI examination.

In the usual care condition children are prepared by the healthcare staff without using any specific equipment or standardized methods.

Study Duration:

36 months

Participant Duration:

All participants need a single visit intervention to complete all study related tasks.

Conditions

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Children, Only Anesthesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

TRIPLE

Caregivers Investigators Outcome Assessors
Participants cannot be blinded due to the nature of the study. The radiologists, anesthesiology team, MRI staff and the second research assistant administering post-procedure questionnaires and coding anesthesiology data intended to be blinded, however, children may disclose their group by talking about their experience.

Study Groups

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VR

Participants in the VR group are immersed in a unique 360° VR experience specifically designed for this study.

The custom made VR experience consists of two parts. In the first part, children find themselves in a simulated MRI room which resembles to the one they will be scanned.

The second half of the VR experience introduces a mindfulness-ACT based meditation segment within the context of a space travel.

Group Type EXPERIMENTAL

VR

Intervention Type OTHER

The virtual environment is provided by the Oculus Quest 2 or 3 VR headset, providing a high-quality and immersive visual experience.

Booklet

Children in the booklet condition will be prepared by using an educational booklet containing colorful illustrations of the MRI examination room and about the procedure. This serves as a resource to familiarize them with the MRI procedure, address common concerns, and provide information about what to expect during the exam. The role of the booklet condition is to serve as an active control for our experimental condition. This condition also contains an interaction with the experimenter and increases familiarity through explanation and illustrations. However, it does not involve the immersive effect of the VR.

Group Type ACTIVE_COMPARATOR

Booklet

Intervention Type OTHER

Children in the booklet condition will be prepared by using an educational booklet containing colorful illustrations of the MRI examination room and about the procedure.

Usual care

In the usual care condition children are prepared by the healthcare staff through explanations, reframing, playing as per personal preference which is currently the standard of care in our departments.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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VR

The virtual environment is provided by the Oculus Quest 2 or 3 VR headset, providing a high-quality and immersive visual experience.

Intervention Type OTHER

Booklet

Children in the booklet condition will be prepared by using an educational booklet containing colorful illustrations of the MRI examination room and about the procedure.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Informed assent and parental informed consent to participate in the study.
2. Stated willingness to participate in the intervention and to complete study questionnaires.
3. Inpatient or outpatient at the Pediatric Center.
4. Age 4-18 years
5. Scheduled for MRI examination under anesthesia at the Semmelweis University.
6. Fluent in Hungarian language

Exclusion Criteria

1. Severe visual impairment or hearing loss that would hinder the participation of the VR and booklet experience.
2. In case of epilepsy, if the treating physician recommend against participation.
3. Children with severe intellectual disability which would hinder participation in the VR group e.g. not able to follow simple instructions.
4. Inpatients, if the treating physician indicates that the child is too unwell for the study.
5. Face or cranial deformities, wounds on the face and head which would hinder wearing the VR headset.
Minimum Eligible Age

4 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Semmelweis University

OTHER

Sponsor Role lead

Responsible Party

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Dr. Horváth Klára

assistant professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Klara Horvath, MD PhD

Role: PRINCIPAL_INVESTIGATOR

Semmelweis University

Locations

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Pediatric Center, Semmelweis University

Budapest, Budapest, Hungary

Site Status RECRUITING

Countries

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Hungary

Central Contacts

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Klara Horvath, MD PhD

Role: CONTACT

0036208259395

Sandor Erdos, MD

Role: CONTACT

036306821793

Facility Contacts

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Klara Horvath, MD PhD

Role: primary

0036208259395

Other Identifiers

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SE RKEB 202/2021

Identifier Type: -

Identifier Source: org_study_id

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