MedDataX Logo

Role of MSCT Volumetry in Assessment of Brain Atrophy in Septic Patients

NCT ID: NCT06112119

Last Updated: 2023-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

55 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-11-01

Study Completion Date

2024-12-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

assessment of brain atrophy associated with septic ICU patients by using MSCT Volumetry

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

ICU Sarcopenia Rates by Abdominal CT: Sepsis vs. Trauma

NCT03982628

Sarcopenia Critical Illness Sepsis +1 more
UNKNOWN

Cerebral Oxygen Challenge of Passive Leg Raising Test in Sepsis

NCT03523169

Critical Illness Sepsis Cerebral Injury
COMPLETED

Sepsis in ICU:Causes and Outcomes in Diabetics and Non Diabetics

NCT05914480

Sepsis
UNKNOWN

The Early Prediction of Sepsis in ICU

NCT05088850

Prediction of Sepsis in Critical Patients
UNKNOWN

Sepsis in ICU:Causes and Outcomes of Sepsis in Diabetics Versus Non Diabetics in Assiut University Hospital

NCT04015752

Septic Shock Sepsis
UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Sepsis is the leading cause of admission to ICU , the number of patients who survive and discharge from ICU has also increased due to technological advances in ICU however quality of life of these patients after ICU discharge is lower than that of healthy people of a similar age, in particular Sepsis associated encephalopathy associated with brain dysfunction.

We hypothesized that brain damage including brain volume reduction that ocurre in acute phase of Sepsis using CT scan and there finding " relationship to risk factor and outcome".

We compared head CT finding at time of admission with those obtained during the course of the treatment

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Sepsis-Associated Encephalopathy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

cohort

patients \>16y with sepsis associated with disturbance in conscious level, the first braun CT scan will be routinely performed on admission, the second further brain CT Scan will be obtained whenever prolonged disturbance of consciousness will be detected.

MSCT

Intervention Type DEVICE

Using Semi-automatic MSCT Volumetry in assessment of brain atrophy associated with septic ICU patients

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

MSCT

Using Semi-automatic MSCT Volumetry in assessment of brain atrophy associated with septic ICU patients

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* patients \>16years old with sepsis associated with disturbance in conscious level admitted to ICU

Exclusion Criteria

* Age\< 16y Brain death Hematological disease Malignant disease Hypoxemia Error in automatic tissue classification Motion artifac
Minimum Eligible Age

16 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Assiut University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Nada Mohamed Abdelmoneim

Assistant Lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Nada mohamed abdelmoneim

Role: PRINCIPAL_INVESTIGATOR

Assiut University

sherif mohamed abdelaal

Role: STUDY_DIRECTOR

Assiut University

samy abdelaziz

Role: STUDY_DIRECTOR

Assiut University

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Nada mohamed abdelmoneim

Role: CONTACT

[email protected]
01097151396

sherif mohamed abdelaal

Role: CONTACT

[email protected]
01003691110

References

Explore related publications, articles, or registry entries linked to this study.

Nakae R, Sekine T, Tagami T, Murai Y, Kodani E, Warnock G, Sato H, Morita A, Yokota H, Yokobori S. Rapidly progressive brain atrophy in septic ICU patients: a retrospective descriptive study using semiautomatic CT volumetry. Crit Care. 2021 Nov 29;25(1):411. doi: 10.1186/s13054-021-03828-7.

Reference Type BACKGROUND
PMID: 34844648 (View on PubMed)

Related Links

Access external resources that provide additional context or updates about the study.

https://doi.org/10.1186/s13054-021-03828-7

retrospective study using semi automatic volumetry

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

sepsis and brain atrophy

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Evaluation of a TDM Program for Intensive Care Patients in the Cerebrospinal Fluid
NCT04426383 COMPLETED
Simple Observational Critical Care Studies
NCT03553069 UNKNOWN
Hemostatic Disorders on Intensive Care Patients.
NCT04179357 UNKNOWN
Neuropathology in Adults Intensive Care Unit Patients With COVID 19
NCT04453670 COMPLETED
Implementation of Apnoea Test for Patients With Suspected Brain Death
NCT06359119 NOT_YET_RECRUITING
Evaluation of Patients With Critical Illness
NCT00100217 COMPLETED
Sepsis Metabolomics
NCT01649440 COMPLETED
Diagnostic and Prognostic Value of Combination Biomarkers in the Critically Ill Patient With Sepsis.
NCT01687010 UNKNOWN
Frequency, Predictors and Outcome of Sepsis Induced Coagulopathy in Critical Care Unit
NCT06586346 NOT_YET_RECRUITING
CharacterisatiON of carDiac funCTion in Intensive Care Unit Survivors of Sepsis.
NCT05633290 UNKNOWN
Musculoskeletal Ultrasound Study in Critical Care: Longitudinal Evaluation
NCT01106300 COMPLETED
Comparative Study for the Validity of Various Severity Scoring System
NCT04683094 COMPLETED
Effect of High volumeHemodiafiltration on Lung Oxygenation
NCT03853005 COMPLETED NA
Machine Learning Predictive Models for Sepsis Risk in ICU Patients With Intracerebral Hemorrhage
NCT06326385 NOT_YET_RECRUITING
Usefulness of Non-invasive Pulse Co-oximetry Haemaglobin Measurements in Critically Ill Black Patients
NCT02035306 COMPLETED NA
Serum Procalcitonin Level May Predict Acute Kidney Injury in ICU Patients With Sepsis
NCT03097393 COMPLETED
Effect of Nutritional Support and Early Rehabilitation on Sepsis
NCT05781971 NOT_YET_RECRUITING NA
Correlation Between Acute Gastrointestinal Injury and Venous Return in Critical Ill Patients
NCT06667297 COMPLETED
ICU Combined Assessment of Cardio-Respiratory Exercise
NCT06193980 RECRUITING
The Gut Microbiome - Source of Sepsis and Novel Target in Intensive Care Units?
NCT06749483 RECRUITING
Thyroid and Cortisol Hormone Response to Sepsis
NCT06289179 NOT_YET_RECRUITING
Optic Nerve Sheath Diameter / Eyeball Transverse Diameter Ratio and Prognosis of Sepsis Associated Encephalopathy
NCT05918705 COMPLETED
Remote Ischemic Preconditioning in Septic Patients
NCT05830669 RECRUITING NA
Efficacy of ICU-VTE Scale in ICU Patients
NCT05487066 COMPLETED
Evaluation of an ICU-specific Questionnaire for Patient-reported Outcome Measures
NCT02767180 COMPLETED