Maximal Rate of Force Development of Ankle Muscles and Functional Ability in Patients With Knee Osteoarthritis

NCT ID: NCT06063889

Last Updated: 2024-08-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

126 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-07-20

Study Completion Date

2024-02-02

Brief Summary

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This study is a detailed assessment of the maximal rate of force development of ankle muscles and its association with functional ability in patients with knee osteoarthritis (OA).

Detailed Description

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This research is designed to study the link between force development in ankle muscles and functional abilities in knee OA patients. It aims to understand the influence of ankle muscle strength, specifically plantar flexors, on the stability, pain, and functionality of patients with knee OA. The study will analyze the rate of force development, its importance in explosive strength improvement, and impact on preventing knee injuries. Furthermore, it will investigate the compensatory mechanism of the plantar flexors developed by patients in advanced stages to balance other muscle failures.

Conditions

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Knee Osteoarthritis Knee Arthritis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Knee OA Patients

This group consists of patients who have been diagnosed with knee osteoarthritis. They will be subjected to a series of tests to assess the maximal rate of force development of ankle muscles and their functional abilities.

Maximal Rate of Force Development Test for Ankle Muscles

Intervention Type DIAGNOSTIC_TEST

This test is designed to measure the maximal rate of force development in the ankle muscles, specifically the plantar flexors. It aims to assess the relationship between the strength of these muscles and the functional ability in patients with knee osteoarthritis. The results from this test will help to understand how lower limb muscle strength influences the symptoms and progression of knee osteoarthritis.

Healthy Control

This group will include healthy individuals without knee osteoarthritis. They will undergo the same series of tests to serve as a control group, enabling the comparison of results with the Knee OA Patients group.

Maximal Rate of Force Development Test for Ankle Muscles

Intervention Type DIAGNOSTIC_TEST

This test is designed to measure the maximal rate of force development in the ankle muscles, specifically the plantar flexors. It aims to assess the relationship between the strength of these muscles and the functional ability in patients with knee osteoarthritis. The results from this test will help to understand how lower limb muscle strength influences the symptoms and progression of knee osteoarthritis.

Interventions

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Maximal Rate of Force Development Test for Ankle Muscles

This test is designed to measure the maximal rate of force development in the ankle muscles, specifically the plantar flexors. It aims to assess the relationship between the strength of these muscles and the functional ability in patients with knee osteoarthritis. The results from this test will help to understand how lower limb muscle strength influences the symptoms and progression of knee osteoarthritis.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Group 1 (Knee OA group)

1. Patients diagnosed with knee osteoarthritis according to Performance of the 2018 classification criteria for early stage knee OA was tested using data from the Osteoarthritis Initiative (OAI (Leung et al.,2020).
2. Grade 2-3 KOA cases according to Kelgren-Lawrance classification
3. Having knee pain for at least 6 months.
4. The visual analog scale (VAS) score being at least 3 or more.
* Group 2 (Healthy control group) 1. Individuals with no signs or symptoms of Knee OA or other neurological or musculoskeletal conditions.

Exclusion Criteria

1. Patellar subluxation
2. Surgery in any joint of the lower limb
3. Meniscal injury
4. Ligament instability
5. Patients who received intra-articular injection in the knee in the last 6 months
6. Patients with problems in the hip and ankle
7. Patients who participated in in another physical therapy program in the last 3 months were not included in the study.
Minimum Eligible Age

30 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ahram Canadian University

OTHER

Sponsor Role lead

Responsible Party

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Mohamed Magdy ElMeligie

Director of Electromyography lab

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Abeer Abdelrahman, Ph.D

Role: STUDY_CHAIR

Cairo University

Locations

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Outpatient clinic of faculty of physical therapy, Ahram Canadian University

Al Ḩayy Ath Thāmin, Giza Governorate, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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012/90002023

Identifier Type: -

Identifier Source: org_study_id

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