Evaluating Artisential Laparoscopic Instruments in Gynecologic Surgery

NCT ID: NCT06050161

Last Updated: 2023-09-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-09-20

Study Completion Date

2027-09-20

Brief Summary

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This study evaluates the efficacy and safety of Artisential laparoscopic instruments in minimally invasive gynecologic surgery.

Detailed Description

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The Artisential laparoscopic instrument is a novel device that allows multi-directional articulation during laparoscopic surgery. There are currently no studies evaluating the efficacy or safety of this device in minimally invasive gynecologic surgery. The investigators aim to compare the efficacy and safety of the Artisential instrument with conventional laparoscopic or robotic instruments.

Patients who are scheduled for a laparoscopic or robotic hysterectomy and/or laparoscopic or robotic sacrocolpopexy will be invited to participate in this study. During the suturing portion of the surgery (either vaginal cuff closure during a hysterectomy, or mesh attachment during a sacrocolpopexy), operating times and safety outcomes will be measured. The approach for vaginal cuff closure will be randomly selected. The approach for mesh attachment suturing will be based on the primary surgical approach (conventional laparoscopy or robotic) and compared to suturing with the Artisential and an internally controlled environment. Therefore, half of the knots placed during a case will be with the Artisential laparoscopic device, and the other half will be placed either with robotic instruments or conventional laparoscopic instruments.

Conditions

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Pelvic Organ Prolapse Abnormal Uterine Bleeding Mesh Augmentation Laparoscopic Surgery Robotic Surgical Suturing Laparoscopic Hysterectomy Minimally Invasive Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Those in the study scheduled for a laparoscopic hysterectomy will be randomly selected for the Artisential vs. Robotic vs. Laparoscopic vaginal cuff closure.

Those in the study scheduled for sacrocolpopexy will have half the mesh sutured on by the primary surgical approach (robotic or laparoscopic) and the other half sutured on by the Artisential laparoscopic instrument
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
The patient will not be told which surgical approaches were used during surgery

Study Groups

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Artisential laparoscopic instrument

Artisential laparoscopic instrument use for suturing during minimally invasive gynecologic surgery

Group Type EXPERIMENTAL

Articulating laparoscopic instrument

Intervention Type DEVICE

The Artisential articulating laparoscopic instrument will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Conventional laparoscopic instrument

Intervention Type DEVICE

Conventional laparoscopic instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Robotic surgical instrument

Intervention Type DEVICE

Robotic surgical instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Conventional laparoscopic instrument

Conventional ("straight stick") laparoscopic instrument use for suturing during minimally invasive gynecologic surgery

Group Type ACTIVE_COMPARATOR

Articulating laparoscopic instrument

Intervention Type DEVICE

The Artisential articulating laparoscopic instrument will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Conventional laparoscopic instrument

Intervention Type DEVICE

Conventional laparoscopic instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Robotic surgical instrument

Intervention Type DEVICE

Robotic surgical instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Robotic instrument

Robotic instrument use for suturing during minimally invasive gynecologic surgery

Group Type ACTIVE_COMPARATOR

Articulating laparoscopic instrument

Intervention Type DEVICE

The Artisential articulating laparoscopic instrument will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Conventional laparoscopic instrument

Intervention Type DEVICE

Conventional laparoscopic instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Robotic surgical instrument

Intervention Type DEVICE

Robotic surgical instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Interventions

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Articulating laparoscopic instrument

The Artisential articulating laparoscopic instrument will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Intervention Type DEVICE

Conventional laparoscopic instrument

Conventional laparoscopic instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Intervention Type DEVICE

Robotic surgical instrument

Robotic surgical instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.

Intervention Type DEVICE

Other Intervention Names

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Artisential Straight stick laparoscopy Da Vinci Robot

Eligibility Criteria

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Inclusion Criteria

* Patient scheduled for robotic or laparoscopic total hysterectomy
* Patient scheduled for robotic or laparoscopic sacrocolpopexy

Exclusion Criteria

* Not a candidate for the above surgical procedures
Minimum Eligible Age

22 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Livs Med

UNKNOWN

Sponsor Role collaborator

Kern Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Yufan Chen

Chief, Division of Urogynecology, Department of Obstetrics and Gynecology

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Yufan B Chen, MD

Role: CONTACT

661-326-2000

Kayvon Milani

Role: CONTACT

661-326-2673

References

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Darwich I, Abuassi M, Weiss C, Stephan D, Willeke F. The Artisential(R) Articulated Laparoscopic Forceps: A Dry Lab Study to Examine Dexterity and Learning Effects in Operators with Different Levels of Laparoscopic Experience. Surg Technol Int. 2021 May 20;38:29-36. doi: 10.52198/21.STI.38.SO1424.

Reference Type BACKGROUND
PMID: 33755941 (View on PubMed)

Jung Y, Hong JI, Han KN, Kim HK. Thoracoscopic anterior mediastinal mass removal using an articulating laparoscopic instrument. Interact Cardiovasc Thorac Surg. 2021 Aug 18;33(3):498. doi: 10.1093/icvts/ivab110. No abstract available.

Reference Type BACKGROUND
PMID: 33880541 (View on PubMed)

Kim A, Lee CM, Park S. Is it Beneficial to Utilize an Articulating Instrument in Single-Port Laparoscopic Gastrectomy? J Gastric Cancer. 2021 Mar;21(1):38-48. doi: 10.5230/jgc.2021.21.e2. Epub 2021 Mar 11.

Reference Type BACKGROUND
PMID: 33854812 (View on PubMed)

Darwich I, Scheidt M, Koliesnikov Y, Willeke F. Laparoscopic low anterior resection performed using ArtiSential(R) in an obese male patient with a narrow pelvis - a video vignette. Colorectal Dis. 2021 Mar;23(3):757-758. doi: 10.1111/codi.15473. Epub 2020 Dec 18. No abstract available.

Reference Type BACKGROUND
PMID: 33275820 (View on PubMed)

Trevis J, Chilvers N, Freystaetter K, Dunning J. Surgeon-Powered Robotics in Thoracic Surgery; An Era of Surgical Innovation and Its Benefits for the Patient and Beyond. Front Surg. 2020 Nov 26;7:589565. doi: 10.3389/fsurg.2020.589565. eCollection 2020.

Reference Type BACKGROUND
PMID: 33330607 (View on PubMed)

Kang SH, Won Y, Lee K, Youn SI, Min SH, Park YS, Ahn SH, Kim HH. Single-Incision Proximal Gastrectomy With Double-Flap Esophagogastrostomy Using Novel Laparoscopic Instruments. Surg Innov. 2021 Feb;28(1):151-154. doi: 10.1177/1553350620958237. Epub 2020 Sep 16.

Reference Type BACKGROUND
PMID: 32938322 (View on PubMed)

Jin HY, Lee CS, Lee YS. Laparoscopic extended right hemicolectomy with D3 lymph node dissection using a new articulating instrument. Tech Coloproctol. 2021 Feb;25(2):235-237. doi: 10.1007/s10151-020-02345-z. Epub 2020 Sep 14. No abstract available.

Reference Type BACKGROUND
PMID: 32926244 (View on PubMed)

Min SH, Cho YS, Park K, Lee Y, Park YS, Ahn SH, Park DJ, Kim HH. Multi-DOF (Degree of Freedom) Articulating Laparoscopic Instrument is an Effective Device in Performing Challenging Sutures. J Minim Invasive Surg. 2019 Dec 15;22(4):157-163. doi: 10.7602/jmis.2019.22.4.157.

Reference Type BACKGROUND
PMID: 35601367 (View on PubMed)

Lee CS, Lee YS. Laparoscopic low anterior resection using new articulating instruments. Tech Coloproctol. 2021 Nov;25(11):1259-1261. doi: 10.1007/s10151-021-02486-9. Epub 2021 Jun 17. No abstract available.

Reference Type BACKGROUND
PMID: 34142257 (View on PubMed)

Kang SH, Cho YS, Min SH, Park YS, Ahn SH, Do Park J, Kim HH. Intracorporeal overlap gastro-gastrostomy for solo single-incision pylorus-preserving gastrectomy in early gastric cancer. Surg Today. 2019 Dec;49(12):1074-1079. doi: 10.1007/s00595-019-01820-x. Epub 2019 May 21.

Reference Type BACKGROUND
PMID: 31115696 (View on PubMed)

Dunning J. Disruptive technology will transform what we think of as robotic surgery in under ten years. Ann Cardiothorac Surg. 2019 Mar;8(2):274-278. doi: 10.21037/acs.2019.03.02.

Reference Type BACKGROUND
PMID: 31032213 (View on PubMed)

Jin HY, Lee CS, Lee YS. Single Incision Laparoscopic Appendectomy Using a New Multi-joint Articulating Instrument. J Gastrointest Surg. 2021 Sep;25(9):2437-2438. doi: 10.1007/s11605-021-05026-w. Epub 2021 May 19. No abstract available.

Reference Type BACKGROUND
PMID: 34013483 (View on PubMed)

Parente G, Thomas E, Cravano S, Di Mitri M, Vastano M, Gargano T, Cerasoli T, Ruspi F, Libri M, Lima M. ArtiSential(R) Articulated Wrist-Like Instruments and Their First Application in Pediatric Minimally Invasive Surgery: Case Reports and Literature Review of the Most Commonly Available Robot-Inspired Devices. Children (Basel). 2021 Jul 17;8(7):603. doi: 10.3390/children8070603.

Reference Type BACKGROUND
PMID: 34356582 (View on PubMed)

Lee E, Lee K, Kang SH, Lee S, Won Y, Park YS, Ahn SH, Suh YS, Kim HH. Usefulness of articulating laparoscopic instruments during laparoscopic gastrectomy for gastric adenocarcinoma. J Minim Invasive Surg. 2021 Mar 15;24(1):35-42. doi: 10.7602/jmis.2021.24.1.35.

Reference Type BACKGROUND
PMID: 35601278 (View on PubMed)

Other Identifiers

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KM23033

Identifier Type: -

Identifier Source: org_study_id

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