Comparisons of Two Airway Clearance Techniques

NCT ID: NCT06032871

Last Updated: 2024-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-03-16

Study Completion Date

2023-12-30

Brief Summary

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The goal of this clinical trial is to compare the effectiveness of two airway clearance techniques for patients with ventilator associated pneumonia. The main questions it aim to answer are:

* effect of the therapies on volume changes
* outcome on sputum clearance Participants will receive airway clearance techniques of
* chest physiotherapy
* high frequency chest wall oscillation.

Detailed Description

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Sputum can be accumulated in the airways of intubated patients, resulting in recurrent pneumonia. The airway clearance therapy is often utilized with chest physiotherapy or high frequency chest wall oscillation which has become popular for its easy of use and less time consuming to the healthcare workers. The main questions it aim to answer are on effectiveness of the therapies on lung volume changes and sputum clearance by two airway clearance techniques. With the oscillation of entire chest wall, the investigators hypothesize that the high frequency chest wall oscillation is more effectively clear sputum in the distal airways.

Conditions

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Airway Clearance Impairment

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

The group will be coded and masked to the investigator and the outcome accessor.

Study Groups

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Chest physiotherapy

Patients receive airway clearance by chest physiotherapy for 30 minutes twice a day.

Group Type EXPERIMENTAL

Chest physiotherapy

Intervention Type PROCEDURE

Participants received chest physiotherapy twice a day

High frequency chest wall oscillation

Participants received high frequency chest wall oscillation therapy twice a dy

Group Type EXPERIMENTAL

high frequency chest wall oscillation

Intervention Type PROCEDURE

Patients receive airway clearance by high frequency chest wall oscillation for 30 minutes twice a day.

Interventions

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high frequency chest wall oscillation

Patients receive airway clearance by high frequency chest wall oscillation for 30 minutes twice a day.

Intervention Type PROCEDURE

Chest physiotherapy

Participants received chest physiotherapy twice a day

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Diagnosed with chronic pulmonary disease
* Diagnosed with ventilator associated pneumonia
* Receive airway clearance therapy

Exclusion Criteria

* Head injury, spinal injury
* Instable hemodynamics
* Intercranial pressure \> 20 cmH2O
* Active hemoptysis
* Empyema
* Eye surgery
* Abdominal distension
* Chest tube insertion
* Active tuberculosis
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hui-Ling Lin

OTHER

Sponsor Role lead

Responsible Party

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Hui-Ling Lin

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Hui-Ling Lin, PhD

Role: PRINCIPAL_INVESTIGATOR

Chang Gung University

Locations

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Linkou Chang Gung Memorial Hospital

Taoyuan District, , Taiwan

Site Status

Chang Gung Memorial Hospital

Taoyuan District, , Taiwan

Site Status

Countries

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Taiwan

References

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Rowley DD, Malinowski TP, Di Peppe JL, Sharkey RM, Gochenour DU, Enfield KB. A Randomized Controlled Trial Comparing Two Lung Expansion Therapies After Upper Abdominal Surgery. Respir Care. 2019 Oct;64(10):1181-1192. doi: 10.4187/respcare.06812. Epub 2019 May 21.

Reference Type RESULT
PMID: 31113857 (View on PubMed)

Other Identifiers

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IRB2212210081

Identifier Type: -

Identifier Source: org_study_id

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