The Relationship of DASH and Mediterranean Diet Score With Serum Adiponectin Levels in Patients With Spinal Cord Injury

NCT ID: NCT05997251

Last Updated: 2023-08-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

66 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-03-01

Study Completion Date

2022-03-01

Brief Summary

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The aim of this study is to reveal the relationship of DASH and Mediterranean diet score with anthropometric measurements and serum adiponectin level in individuals with spinal cord injury. This research was planned as a cross-sectional, case-control study. With the data to be obtained from the research, information will be obtained about the hormonal or biochemical basis of metabolic disorders such as atherosclerosis and insulin resistance that may occur in individuals with spinal cord injury in the long term.

20 individuals with Spinal Cord Injury will be included in the study, and the results of the patients will be compared with 20 healthy individuals. In order to determine the food consumption status of the patients, a 1-day food consumption record will be requested. DASH diet score and Mediterranean diet score will be calculated from dietary records. After 8 hours of fasting, 3 ml of peripheral blood will be taken for the measurement of adiponectin between 08:00 and 09:00 in the morning from the individuals in the study and control groups. Adiponectin level will be measured and its correlation with DASH diet score and Mediterranean diet score will be examined.

Detailed Description

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Conditions

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Spinal Cord Injuries

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Patients with spinal cord injury

Keeping a 1-day food consumption record by the patient

Intervention Type OTHER

Checking and receiving the 1-day food consumption record recorded by the patient by the researcher

Measurement of adiponectin level

Intervention Type OTHER

Adiponectin level will be measured for each group

Healthy group

Keeping a 1-day food consumption record by the patient

Intervention Type OTHER

Checking and receiving the 1-day food consumption record recorded by the patient by the researcher

Measurement of adiponectin level

Intervention Type OTHER

Adiponectin level will be measured for each group

Interventions

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Keeping a 1-day food consumption record by the patient

Checking and receiving the 1-day food consumption record recorded by the patient by the researcher

Intervention Type OTHER

Measurement of adiponectin level

Adiponectin level will be measured for each group

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Having spent at least 6 months after spinal cord injury
* 1st motor neuron injury
* Being between the ages of 18-65
* Being between the ages of 18-65
* Giving consent to participate in the study

Exclusion Criteria

* Having an additional disease to the spinal cord injury
* Having a 2nd motor neuron lesion


• Having any disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ankara City Hospital Bilkent

OTHER

Sponsor Role lead

Responsible Party

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Emre Adıgüzel

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ankara Bilkent City Hospital Physical Treatment and Rehabilitation Hospital

Ankara, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Wang YH, Huang TS, Liang HW, Su TC, Chen SY, Wang TD. Fasting serum levels of adiponectin, ghrelin, and leptin in men with spinal cord injury. Arch Phys Med Rehabil. 2005 Oct;86(10):1964-8. doi: 10.1016/j.apmr.2005.04.017.

Reference Type BACKGROUND
PMID: 16213239 (View on PubMed)

Ekmekci H, Ekmekci OB. The role of adiponectin in atherosclerosis and thrombosis. Clin Appl Thromb Hemost. 2006 Apr;12(2):163-8. doi: 10.1177/107602960601200203.

Reference Type BACKGROUND
PMID: 16708117 (View on PubMed)

O'Brien LC, Graham ZA, Chen Q, Lesnefsky EJ, Cardozo C, Gorgey AS. Plasma adiponectin levels are correlated with body composition, metabolic profiles, and mitochondrial markers in individuals with chronic spinal cord injury. Spinal Cord. 2018 Sep;56(9):863-872. doi: 10.1038/s41393-018-0089-8. Epub 2018 Mar 20.

Reference Type BACKGROUND
PMID: 29559683 (View on PubMed)

Other Identifiers

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E2-21-89

Identifier Type: -

Identifier Source: org_study_id

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