Muscle Strength, Muscle Endurance, Lower Extremity Function, Aerobic Capacity, Pressure Pain Threshold and Edema in Women with Lipedema

NCT ID: NCT06866847

Last Updated: 2025-03-10

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 30 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-01-10
• Study Completion Date: 2025-12-31

Brief Summary

Lipedema is a chronic progressive disease that causes disproportionate, painful extremities with abnormal fat distribution. Lipedema is known to cause physical and psychosocial disorders in individuals, but there are very limited studies on this subject. The aim of this study is to evaluate muscle strength, muscle endurance, lower extremity function, aerobic capacity, pressure pain threshold and edema parameters in individuals diagnosed with lipedema and to compare them with individuals without lipedema. Volunteer women aged 18 years and older with lipedema (study group) and without lipedema (control group) will be included in the study. After recording the demographic information of the patients, lower extremity muscle strength will be assessed with the K-force handheld dynamometer, lower extremity muscle endurance with the 30 Second Sit-to-Stand Test, lower extremity function with the Lower Extremity Functional Scale, aerobic capacity with the 6-Minute Walking Test, pressure pain threshold with the Baseline algometer, and edema with the moisturemeter. Data from the study and control groups will be recorded in the SPSS program and compared using the appropriate statistical method.

Conditions

Lipedema; Healthy

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: PROSPECTIVE

Study Groups

study group

Women diagnosed with lipedema

No interventions assigned to this group

control group

Women over the age of 18 who do not have any cardiovascular, orthopedic and/or neurological problems that may affect physical capacity and who do not have diseases such as heart failure or renal failure that may cause general or localized edema.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Women over the age of 18 diagnosed with lipedema

Exclusion Criteria

• Having cardiovascular, orthopedic and/or neurological problems that may affect physical capacity

• Having diseases such as heart failure, kidney failure that may cause general or localized edema

• Minimum Eligible Age: 18 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: Yes

Sponsors

Gazi University

OTHER

Sponsor Role: lead

Responsible Party

Ilke Keser

Prof. Dr.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Gazi University Faculty of Health Sciences

Ankara, , Turkey (Türkiye)

Site Status: RECRUITING

Countries

Turkey (Türkiye)

Central Contacts

Miray Haspolat, Doctor of Philosophy

Role: CONTACT

miraybalaman@gmail.com

+ 90 542 792 2639

Facility Contacts

Ilke Keser, Prof. Dr.

Role: primary

ilkekeser@gazi.edu.tr

+90 506 669 9808

Other Identifiers

Lipedema/Haspolat M

Identifier Type: -

Identifier Source: org_study_id