Complex Decongestive Applications in Patients With Lipedema

NCT ID: NCT04492046

Last Updated: 2020-07-30

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 23 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2019-09-02
• Study Completion Date: 2020-02-12

Brief Summary

Lipedema is a rare condition which almost exclusively affects women. The disease is characterized with bilateral, symmetric abnormal accumulation of subcutaneous fat and is often mistaken for simple obesity. In most patients, the hips, buttocks, thighs, knees, and lower legs are affected. Upper extremity involvement has been reported to be present in 80% patients. The hands and feet are never affected. The accumulation of subcutaneous fat and edema results in tenderness, sensitivity to touch and pressure and also pain. Patients also tend to bruise easily even after a minimal trauma. It has been reported that the complaint of pain increases with aging.There is no known cure for lipedema. However, conservative treatment with physiotherapy, manual lymph drainage and compression, also known as complex decongestive physiotherapy is used worldwide as a standard treatment regimen . The aim of this study is to investigate the effect of complex decongestive applications on lower extremity limb circumference and volume in patients with lipedema.

Detailed Description

All participants included in the study were included in a treatment protocol consisting of complex decongestive physiotherapy Each patient received;

1. 45 minutes of manual lymph drainage on both lower extremities,

2. Moisturisation of the lower extremities,

3. Bandage application

Alongside this routine, the patients were advised to exercise (walk) regularly every day.

This treatment routine was continued until the patients were discharged from the clinic.

Conditions

Lipedema

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: PROSPECTIVE

Study Groups

Complex Decongestive physiotherapy

All participants included in the study were included in a treatment protocol consisting of Complex Decongestive physiotherapy.

Manual Lymph Drainage

Intervention Type: OTHER

Manual lymph drainage is an effective therapeutic method used in the conservative treatment of lipedema. The application was performed on both lower extremities for 45 minutes.

Bandaging

Intervention Type: OTHER

Multilayered compression bandaging techniques have an assisting role in the further reduction of the volume of the limb and enhance the continuous pump mechanism via the active involvement of muscle pumps. All patients received bandages following Manual lymph drainage application.

Interventions

Manual Lymph Drainage

Manual lymph drainage is an effective therapeutic method used in the conservative treatment of lipedema. The application was performed on both lower extremities for 45 minutes.

Intervention Type: OTHER

Bandaging

Multilayered compression bandaging techniques have an assisting role in the further reduction of the volume of the limb and enhance the continuous pump mechanism via the active involvement of muscle pumps. All patients received bandages following Manual lymph drainage application.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Being willing to participate in the study
• Being 18-65 years old
• Having a diagnosis of lower extremity lipedema

Exclusion Criteria

• Having edematous disease in the lower extremity such as lymphedema or chronic venous insufficiency

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Gazi University

OTHER

Sponsor Role: lead

Responsible Party

Gokhan Yazici

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Gokhan Yazici, PhD

Role: PRINCIPAL_INVESTIGATOR

Gazi University

Locations

Gazi University

Ankara, Çankaya, Turkey (Türkiye)

Countries

Turkey (Türkiye)

References

Volkan-Yazici M, Yazici G, Esmer M. The Effects of Complex Decongestive Physiotherapy Applications on Lower Extremity Circumference and Volume in Patients with Lipedema. Lymphat Res Biol. 2021 Feb;19(1):111-114. doi: 10.1089/lrb.2020.0080. Epub 2020 Oct 30.

Reference Type: DERIVED

PMID: 33124947 (View on PubMed)

Other Identifiers

Lipedema

Identifier Type: -

Identifier Source: org_study_id