Registry of Multicenter Brain-Heart Comorbidity in China

NCT ID: NCT05961748

Last Updated: 2023-09-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-01-01

Study Completion Date

2032-12-31

Brief Summary

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This study is a multi-center, prospective, registry study. This research was supported by the National Key Research and Development Program. To establish a domestic multi-center, large-scale "brain-heart comorbidity" dynamic database platform including clinical, sample database, image and other multi-dimensional information requirements, through the construction of a multi-center intelligent scientific research integration platform based on artificial intelligence.

Any of newly diagnosed cardiovascular related diseases were identified via ICD-10-CM codes: I21, I22, I24 (Ischaemic heart diseases) \[i.e., ACS\], I46 (cardiac arrest), I48 (Atrial fibrillation/flutter), I50 (Heart failure), I71 (Aortic disease), I60 (subarachnoid hemorrhage), I61 (intracerebral hemorrhage), I63 (Cerebral infarction), I65 (Occlusion and stenosis of precerebral arteries), I66 (Occlusion and stenosis of cerebral arteries), I67.1 (cerebral aneurysm), I67.5 (moyamoya diseases), Q28.2 (Arteriovenous malformation of cerebral vessels).

The data is stored on the brain-heart comorbidity warehouse via a physical server at the institution's data centre or a virtual hosted appliance. The brain-heart comorbidity platform comprises of a series of these appliances connected into a multicenter network. This network can broadcast queries to each appliance. Results are subsequently collected and aggregated. Once the data is sent to the network, it is mapped to a standard and controlled set of clinical terminologies and undergoes a data quality assessment including 'data cleaning' that rejects records which do not meet the brain-heart comorbidity quality standards. The brain-heart comorbidity warehouse performs internal and extensive data quality assessment with every refresh based on conformance, completeness, and plausibility (http://10.100.101.65:30080/login).

Detailed Description

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Conditions

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Ischemic Heart Disease Cardiac Arrest Atrial Fibrillation Heart Failure Aortic Diseases Subarachnoid Hemorrhage Intracerebral Hemorrhage Cerebral Infarction Occlusion and Stenosis of Precerebral Arteries Occlusion and Stenosis of Cerebellar Arteries Cerebral Aneurysm Moyamoya Disease Arteriovenous Malformation of Cerebral Vessels

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Multi-disciplinary assessment

Multi-disciplinary assessment

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* age \> 18 years old
* Any of newly diagnosed cardiovascular-related diseases were identified via ICD-10-CM codes: I21, I22, I24 (Ischaemic heart diseases) \[i.e., ACS\], I46 (cardiac arrest), I48 (Atrial fibrillation/flutter), I50 (Heart failure), I71 (Aortic disease), I60 (subarachnoid hemorrhage), I61 (intracerebral hemorrhage), I63 (Cerebral infarction), I65 (Occlusion and stenosis of precerebral arteries), I66 (Occlusion and stenosis of cerebral arteries), I67.1 (cerebral aneurysm), I67.5 (moyamoya diseases), Q28.2 (Arteriovenous malformation of cerebral vessels).

Exclusion Criteria

·refuse to participate in the registry
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Beijing Tiantan Hospital

OTHER

Sponsor Role lead

Responsible Party

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Xiaolin Chen, MD

Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Shuo Wang, MD

Role: STUDY_CHAIR

Beijing Tiantan Hospital

Yong Cao, MD

Role: STUDY_DIRECTOR

Beijing Tiantan Hospital

Dong Xu, MD

Role: PRINCIPAL_INVESTIGATOR

Beijing Tiantan Hospital

Zening Jin, MD

Role: PRINCIPAL_INVESTIGATOR

Beijing Tiantan Hospital

Hao Wang, MD

Role: PRINCIPAL_INVESTIGATOR

Beijing Tiantan Hospital

Shuai Kang, MD

Role: PRINCIPAL_INVESTIGATOR

Beijing Tiantan Hospital

Yu Chen, MD

Role: PRINCIPAL_INVESTIGATOR

Beijing Tiantan Hospital

Qingyuan Liu, MD

Role: PRINCIPAL_INVESTIGATOR

Beijing Tiantan Hospital

Runting Li, MD

Role: PRINCIPAL_INVESTIGATOR

Beijing Tiantan Hospital

Heze Han, MD

Role: PRINCIPAL_INVESTIGATOR

Beijing Tiantan Hospital

Wenxiong Song, MD

Role: PRINCIPAL_INVESTIGATOR

Beijing Tiantan Hospital

Jionghao Xue, MD

Role: PRINCIPAL_INVESTIGATOR

Beijing Tiantan Hospital

Minghao Liu, MD

Role: PRINCIPAL_INVESTIGATOR

Beijing Tiantan Hospital

Locations

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Beijing Tiantan Hospital, Capital Medical University

Beijing, Beijing Municipality, China

Site Status RECRUITING

Beijing Anzhen Hospital, Capital Medical University

Beijing, Beijing Municipality, China

Site Status NOT_YET_RECRUITING

Beijing Chaoyang Hospital, Capital Medical University

Beijing, Beijing Municipality, China

Site Status NOT_YET_RECRUITING

Chinese People's Liberation Army (PLA) General Hospital

Beijing, Beijing Municipality, China

Site Status NOT_YET_RECRUITING

Peking University First Hospital

Beijing, Beijing Municipality, China

Site Status NOT_YET_RECRUITING

Xuanwu Hospital, Capital Medical University

Beijing, Beijing Municipality, China

Site Status NOT_YET_RECRUITING

The First Affiliated Hospital of Fujian Medical University

Fuzhou, Fujian, China

Site Status NOT_YET_RECRUITING

The First Affiliated Hospital of Xiamen University

Xiamen, Fujian, China

Site Status NOT_YET_RECRUITING

Shenzhen Qianhai Shekou Free Trade Zone Hospital

Shenzhen, Guangdong, China

Site Status NOT_YET_RECRUITING

The First Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, China

Site Status NOT_YET_RECRUITING

The First Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, China

Site Status NOT_YET_RECRUITING

Huashan Hospital of Fudan University

Shanghai, Shanghai Municipality, China

Site Status NOT_YET_RECRUITING

Shanxi Provincial People's Hospital

Shanxi, Shanxi, China

Site Status NOT_YET_RECRUITING

The Second Affiliated Hospital of Kunming Medical University

Kunming, Yunnan, China

Site Status NOT_YET_RECRUITING

Countries

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China

Central Contacts

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Xiaolin Chen, MD

Role: CONTACT

13810624845

Fa Lin, MD

Role: CONTACT

13681107240

Facility Contacts

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Fa Lin, MD

Role: primary

13681107240

Ming Gong, MD

Role: primary

Hai Gao, MD

Role: backup

Xiaojuan Guo, MD

Role: primary

Hang Zhu, MD

Role: primary

Wei Ma, MD

Role: primary

Xinggang Wang, MD

Role: backup

Yingqi Xing, MD

Role: primary

Dezhi Kang, MD

Role: primary

Sifang Chen, MD

Role: primary

Zhiwei Wang, MD

Role: primary

Huaizhang Shi, MD

Role: primary

Dongming Yan, MD

Role: primary

Guosheng Zhou, MD

Role: backup

Bin Xu, MD

Role: primary

Feng Xu, MD

Role: backup

Shaohua Ren, MD

Role: primary

Jun Pu, MD

Role: primary

Other Identifiers

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KY2022-221-02

Identifier Type: -

Identifier Source: org_study_id

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