A Registry of Cardiac PET and CardioFlux Magnetocardiography in Patients With Suspected Coronary Ischemia.

NCT ID: NCT05868902

Last Updated: 2025-02-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-08-28

Study Completion Date

2025-12-31

Brief Summary

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A multicenter observational data development registry collecting diagnostic measures via standard of care (SOC) cardiac PET in order gain a better understanding of how CardioFlux MCG may be used in the detection of coronary ischemia.

Detailed Description

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Conditions

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Coronary; Ischemic

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Negative Cardiac PET

Participants without clinical significant findings for coronary ischemia on cardiac PET scan.

CardioFlux Magnetocardiography

Intervention Type DEVICE

The device is a magnetocardiography (MCG) scanner named CardioFlux, which is paired with a cloud processing software. CardioFlux devices are owned by Genetesis and are currently cleared for the acquisition, display, and analysis of magnetic fields generated by cardiac electrical activity (K182571, FDA clearance letter available for download online)

Positive Cardiac PET

Participants with findings indicative of coronary ischemia on cardiac PET scan.

CardioFlux Magnetocardiography

Intervention Type DEVICE

The device is a magnetocardiography (MCG) scanner named CardioFlux, which is paired with a cloud processing software. CardioFlux devices are owned by Genetesis and are currently cleared for the acquisition, display, and analysis of magnetic fields generated by cardiac electrical activity (K182571, FDA clearance letter available for download online)

Interventions

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CardioFlux Magnetocardiography

The device is a magnetocardiography (MCG) scanner named CardioFlux, which is paired with a cloud processing software. CardioFlux devices are owned by Genetesis and are currently cleared for the acquisition, display, and analysis of magnetic fields generated by cardiac electrical activity (K182571, FDA clearance letter available for download online)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Willing to provide informed consent
* Male or female, aged 40 and up (inclusive) at the time of enrollment
* Clinical suspicion of myocardial ischemia that clinician desired cardiac PET
* Completed cardiac PET within 2 weeks prior to study enrollment

Exclusion Criteria

* Patients unable to fit into CardioFlux device.
* Patients unable to lie supine for 5 minutes.
* Patients with implanted ferromagnetic objects above the costal margin of the rib cage (implanted pacemakers, cardioverter/defibrillators, infusion pumps, and/or neuro stimulators). NOTE: Sternotomy wires stents are acceptable
* Ongoing atrial fibrillation or atrial flutter
* Life expectancy \<1 yrs. due to non-cardiovascular comorbidity
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Genetesis Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Cleveland Clinic

Cleveland, Ohio, United States

Site Status RECRUITING

Kettering Health

Kettering, Ohio, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Zoe E Swann, PhD

Role: CONTACT

4802868695

Robert Takla, MD

Role: CONTACT

Facility Contacts

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Cynthia Rosser

Role: primary

(216) 444-4372

Allison Dymacek

Role: primary

Other Identifiers

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1000-8

Identifier Type: -

Identifier Source: org_study_id

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