Safety and Efficacy of High Flow Nasal Canula in Patients With Mild Hypercapnia

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-01

Study Completion Date

2023-07-01

Brief Summary

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Evaluate safety and efficacy of application ( high flow nasal canula) in cases with mild hypercapnia, included 30 patients who were hospitalized in Mansoura University chest department with mild Hypercapnia (Pco2 range 45-60 mmhg and power of hydrogen not less 7.30) of different pulmonary disease categories (Chronic obstructive pulmonary disease acute exacerbation, pneumonia, Interstitial lung diseases, etc).

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Detailed Description

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Conditions

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Hypercapnia

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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with mild Hypercapnia (Pco2 range 45-60 mmhg and power of hydrogen not less 7.30)

with mild Hypercapnia (Pco2 range 45-60 mmhg and power of hydrogen not less 7.30) of different pulmonary disorders

Group Type EXPERIMENTAL

high flow nasal canula

Intervention Type DEVICE

administration of high flow nasal canula at initial flow 35 liters per minute and Fio2 (fraction of inspired oxygen of 50%) with titration to reach oxygen saturation of 88-92%.

Interventions

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high flow nasal canula

administration of high flow nasal canula at initial flow 35 liters per minute and Fio2 (fraction of inspired oxygen of 50%) with titration to reach oxygen saturation of 88-92%.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* patients with mild Hypercapnia

Exclusion Criteria

* Excluded cases had age less than 18 years or pediatric group .
* patients with their mental state altered, confused, comatose, severe agitation or non cooperative
* Cases with moderate or severe Hypercapnia
* cases in need for immediate invasive mechanical ventilation
* cases with respiratory rate more than 35 breath per minute.
* cases with Respiratory exhaustion , fatigue , excess use of respiratory accessory muscles
* Shock , hemodynamic instability, post arrest cases,
* cases with facial trauma or severe nasal deformity,
* Patients with sleep breathing disorders or upper airway obstruction
* patients with history of home ventilation prior admission

Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No