Magnesium as an Adjuvant Agent for Postoperative Pain

NCT ID: NCT05947760

Last Updated: 2025-10-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE4

Total Enrollment

64 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-03-10

Study Completion Date

2026-04-01

Brief Summary

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Participants are being asked to participate in this research study because they have elected to undergo periacetabular osteotomy (PAO). This research study is looking at if using IV magnesium during surgery can help to reduce pain after surgery.

Detailed Description

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Conditions

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Pain, Postoperative

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Participants

Study Groups

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IV Magnesium Sulfate adjuvant group

Participants in this group will receive standard-of-care procedures intraoperatively and postoperatively along with IV magnesium sulfate for pain control.

Group Type EXPERIMENTAL

IV Magnesium Sulfate

Intervention Type DRUG

Participants will receive IV Magnesium Sulfate intraoperatively.

Control group

Participants in this group will receive standard-of-care procedures intraoperatively and post-operatively for pain control.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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IV Magnesium Sulfate

Participants will receive IV Magnesium Sulfate intraoperatively.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients undergoing periacetabular osteotomy with or without adjuvant hip arthroscopy

Exclusion Criteria

* illiterate or non-English speaking patients
* patients with 2nd or 3rd degree AV block
* patients with severe renal insufficiency
* patients with heart failure
* patients with bradycardia
Minimum Eligible Age

14 Years

Maximum Eligible Age

89 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospitals Cleveland Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Robert Wetzel, MD

Orthopedic Trauma Surgeon

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Robert Wetzel, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospitals

Locations

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University Hospitals

Cleveland, Ohio, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Alex Nighswander

Role: CONTACT

216-844-3190

Facility Contacts

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Elika Fanaeian, MS

Role: primary

7608846031

Other Identifiers

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STUDY20230720

Identifier Type: -

Identifier Source: org_study_id

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