The Effect of Intraoperative Magnesium Sulfate Infusion on the Postoperative Recovery

NCT ID: NCT03206008

Last Updated: 2018-04-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

11 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-11-18

Study Completion Date

2017-11-24

Brief Summary

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Evaluating analgesic effect of intraoperative magnesium sulfate infusion in the outpatient surgery case

Detailed Description

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Conditions

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Postoperative Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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Normal saline group

after loading normal saline 100cc in 10-20 minutes, continuous infusion of normal saline until the end of surgery

Group Type PLACEBO_COMPARATOR

Normal saline

Intervention Type DRUG

Placebo

Magnesium group

after loading magnesium sulfate dosing 50 mg/kg (100cc) in 10-20 minutes, continuous infusion of magnesium sulfate 15 mg/kg/h until the end of surgery

Group Type ACTIVE_COMPARATOR

Magnesium Sulfate

Intervention Type DRUG

Interventions

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Magnesium Sulfate

Intervention Type DRUG

Normal saline

Placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* aged between 18-65 year-old-patient (ASA I-II) who are planned to undergoing day surgery

Exclusion Criteria

* ASA class ≥ III
* suspected imbalance of electrolyte
* myocardial damage or conduction delay
* myasthenia gravis or other neuromuscular disease
* impaired renal function
* already using any type of analgesia
* denial of participating in the study or not giving the informed consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Seoul National University Bundang Hospital

OTHER

Sponsor Role lead

Responsible Party

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LEE YEA JI

clinical professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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SangHwan Do

Role: STUDY_CHAIR

Seoul National University Bundang Hospital

Locations

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Seoul National University Bundang Hospital, department of Anesthesia and pain

Seongnam, Gyenggo-do, South Korea

Site Status

Countries

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South Korea

Other Identifiers

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B-1608-360-006

Identifier Type: -

Identifier Source: org_study_id

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