MicroRNAs From Blood Samples as Biomarkers for Gastric Cancer Detection

NCT ID: NCT05901376

Last Updated: 2023-06-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

280 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-04-25

Study Completion Date

2025-06-30

Brief Summary

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The goal of this observational study is to compare specific microRNA levels from the plasma of gastric cancer patients and healthy volunteers to see if there is an upregulated expression in gastric cancer patients.

The main question it aims to answer is:

\- Can microRNAs be effectively used as diagnostic biomarkers for gastric cancer?

Participants will be asked for their consent to obtain 5 cc of blood.

Detailed Description

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Conditions

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Gastric Cancer MicroRNAs

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Gastric Cancer

MicroRNA

Intervention Type DIAGNOSTIC_TEST

MiR-20a, MiR-21, MiR-106b, MiR-199a, MiR-223

Control

MicroRNA

Intervention Type DIAGNOSTIC_TEST

MiR-20a, MiR-21, MiR-106b, MiR-199a, MiR-223

Interventions

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MicroRNA

MiR-20a, MiR-21, MiR-106b, MiR-199a, MiR-223

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Recently diagnosed gastric cancer
* Never received any treatment for gastric cancer


* Age 50 or above
* Underwent elective upper gastrointestinal endoscopy and negative for gastric cancer
* No prior history of gastric dysplasia or cancer

Exclusion Criteria

* Patients who cannot give informed consent
* Pregnancy
* Lymphoma
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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King Chulalongkorn Memorial Hospital

OTHER

Sponsor Role lead

Responsible Party

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Rapat Pittayanon

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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King Chulalongkorn Memorial Hospital

Bangkok, Not Required For This Country, Thailand

Site Status RECRUITING

Countries

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Thailand

Central Contacts

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Rapat Pittayanon

Role: CONTACT

+662564000

Kanik Sritara

Role: CONTACT

+66825254000

Facility Contacts

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Rapat Pittayanon, MD

Role: primary

022564000

Other Identifiers

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RP023

Identifier Type: -

Identifier Source: org_study_id

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