Sodium Channel Mutations in Patient With the Anterior Cutaneous Nerve Entrapment Syndrome (ACNES)
NCT ID: NCT05877274
Last Updated: 2023-10-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
50 participants
OBSERVATIONAL
2023-10-03
2024-12-31
Brief Summary
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The primary objective is to determine if there are mutations of Nav1.7 and Nav1.8 in patients with ACNES. Therefore, one blood sample will be drawn, in which the mutations will be analyzed.
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Detailed Description
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Conditions
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Study Design
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COHORT
CROSS_SECTIONAL
Study Groups
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Patients with ACNES
Patients with ACNES who fulfill the inclusion criteria.
Sodium channel mutation
Mutation of the genes SCN9A and SCN10A, which encode for Sodium channel 1.7 and 1.8.
Interventions
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Sodium channel mutation
Mutation of the genes SCN9A and SCN10A, which encode for Sodium channel 1.7 and 1.8.
Eligibility Criteria
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Inclusion Criteria
* Known to have a first- or second-degree relative with ACNES;
* Have more than one recurrence of ACNES after a pain free period or ACNES at multiple locations in the abdominal wall;
* Persistent pain after posterior neurectomy.
Exclusion Criteria
* Known neuromuscular or neurodegenerative disease.
18 Years
ALL
No
Sponsors
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Maxima Medical Center
OTHER
Responsible Party
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dr. RMH Roumen, surgeon
Head of surgery, Principal Investigator
Principal Investigators
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Rudi Roumen, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Maxima Medical Center
Locations
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Maxima Medical Center
Veldhoven, , Netherlands
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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NL84021.015.23
Identifier Type: -
Identifier Source: org_study_id
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