The Effect of Non-Surgical Periodontal Treatment on Bone Metabolism in Type 2 Diabetes and Systemically Healthy Individuals
NCT ID: NCT05862311
Last Updated: 2023-05-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
50 participants
INTERVENTIONAL
2020-03-12
2021-03-12
Brief Summary
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Detailed Description
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Method: Within the scope of this study, applying to Necmettin Erbakan University Faculty of Dentistry Periodontology Clinic; A total of 50 individuals, including 25 patients with type 2 diabetes and periodontitis (DMP group) and 25 patients with systemically healthy and periodontitis (SSP group), were included in the study. After recording the clinical periodontal parameters (gingival index (GI), plaque index (PI), probing pocket depth (PPD), clinical attachment level (CAL)) of each individual included in the study, GCF samples were obtained and non-surgical periodontal therapy were completed. The individuals were invited to the controls 3 months later and the procedures for clinical periodontal measurements and DOS samples collection were repeated. Levels of biomarkers in DOS samples were determined by ELISA (Enzyme Linked Immunosorbent Assay) method.
Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
DIAGNOSTIC
NONE
Study Groups
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systemically healthy and periodontitis
ELISA
ELISA(enzyme-linked immunosorbent assay)
type 2 diabetes and periodontitis
ELISA
ELISA(enzyme-linked immunosorbent assay)
Interventions
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ELISA
ELISA(enzyme-linked immunosorbent assay)
Eligibility Criteria
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Inclusion Criteria
* Individuals between the ages of 18-65
* Diagnosed as stage 2 or stage 3 periodontitis as a result of periodontal examination
* Those who do not have predisposing factors (restoration, caries, etc.)
Exclusion Criteria
* Any periodontal treatment performed in the last 6 months,
* Being in pregnancy and/or lactation period,
* Individuals who had received any anti-inflammatory, antibiotic, antioxidant or corticosteroid treatment in the last 6 months and refused to participate in the study were excluded from the study.
18 Years
65 Years
ALL
Yes
Sponsors
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Necmettin Erbakan University
OTHER
Responsible Party
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Ummuhan Tekin Atay
principal investigator
Locations
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Necmettin Erbakan University
Konya, , Turkey (Türkiye)
Countries
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Other Identifiers
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Ummuhantekinatay.
Identifier Type: -
Identifier Source: org_study_id
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