Benefit of Hypnosis on Smartphone for Acute Post-operative Pain (HYPNO-APP)

NCT ID: NCT05854914

Last Updated: 2025-08-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-06-19

Study Completion Date

2026-06-30

Brief Summary

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Appendicitis is a common pathology and the one of the most common surgical procedures performed in France. Young subjects are the most frequent patients with appendicitis. Appendicular peritonitis increases post-operative pain, morbidity, and the average length of hospital stay compared to uncomplicated appendicitis.

Pain alters perioeprative rehabilitation of patients. Surgery, performed urgently, generates more anxiety and pain than scheduled surgery. But, intensity of chronic postoperative pain is in correlation to intensity of acute postoperative pain. In addition, admission of emergency cases is more axiety-inducing, due to wait times, packed emergency room, worklaod of medical staff.

Sex and age also modify perception of postoperative pain. Adults under 50 feel more pain than older patients for similar procedures.

Medication for pain is required in perioperative period et is administered according protocol of each medical center ; these protocols include analgesics, opioids or not, benzodiazepine... However, opioids analgesic (example: morphine) can induce side effect, such as confusional syndrome, cardio-pulmonary manifestations, ileus, nausea and vomiting...

Non-pharmacological approaches have been also proposed to reduce anxiety and pain. Hypnosis is frequently used but not always adapted to the emergency: need for qualified and available staff, environment not conducive to hypnotic induction...

Hypnosis is a modified state of consciousness ; it is neither a state of vigilance nor a state of sleep. Several types of hypnosis can be distinguished according to the medical application, such as hypnoanalgesia or hypnosedation.

Using hypnosedation during surgical or invasive procedure can reduce the use of painkillers and sedatives. Interest of hypnosis has been observed for extraction of wisdow teeth, delivery...

Young patients are very comfortable with the use of their smartphone which is often the first object recovered when they return from the operating room. Many hypnosis videos are available free of charge on Internet, and some of which are produced by specialized practitioners and university teachers.

A recent study has shown that among young people, addiction to smartphone is a predisposition to hypnosis.

However, the use of hypnosis videos on smartphone has never been studied for the control of postoperative pain.

Detailed Description

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Conditions

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Appendicitis With Peritonitis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Hypnosis video to control postoperative pain.

Group Type EXPERIMENTAL

Use of hypnosis videos

Intervention Type PROCEDURE

Hypnosis on smartphone will be used to manage pain for emergent coelioscopy surgery of patients with acute and complicated appendicitis, with generalized peritonitis

Interventions

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Use of hypnosis videos

Hypnosis on smartphone will be used to manage pain for emergent coelioscopy surgery of patients with acute and complicated appendicitis, with generalized peritonitis

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients aged 18 years and over
* Complicated acute appendicitis with generalized appendicitis, coelioscopy emergency surgery
* Signature of the written informed consent form by the patient
* Affiliation to a French health insurance scheme or equivalent
* Patient inderstands French and has a smartphone with internet access


* Uncomplicated or complicated appendicitis of abscesses, presence of an intraperitoneal abscess, a plastron, uncomplicated appendicitis of generalized peritonitis
* Patient with a neurological, visual or auditory condition where videos cannot be viewed
* Presence of active cancer, a malignant hemopathy, drug addiction, coagulopathy, immunosuppressive treatment
* Non-acute or interval appendectomy, i.e. after antibiotic treatment of a complicated appendicitis of the plastron or drainage of an appendicular abscess;
* Vulnerable people: adult under guardianship, curator ship or deprived of freedom.
* Medication or pathology affecting ability to discern: Severe psychotic disorders
* Patient refusing to monitor anxiety and pain via smartphone
* Patient already medically monitored for anxiety, depressive or chronic pain syndrome
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Nice

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Nice University Hospital

Nice, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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MASSALOU Damien

Role: CONTACT

04 92 03 33 13 ext. +33

Facility Contacts

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MASSALOU Damien

Role: primary

0492033313 ext. +33

Other Identifiers

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21-AOIP-05

Identifier Type: -

Identifier Source: org_study_id

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