Attenuation of the Hemodynamic Response to Double-lumen Endotracheal Intubation With Nebulized Lidocaine
NCT ID: NCT05850702
Last Updated: 2023-05-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
92 participants
INTERVENTIONAL
2023-06-15
2025-09-09
Brief Summary
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The main question it aims to answer is to evaluate the changes in mean arterial pressure after intubation.
Participants will inhale 5ml of 2% lidocaine by nebulization15min before intubation.
Researchers will compare saline group to see if saline effects
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
QUADRUPLE
Study Groups
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lidocaine
Intervention group
Lidocaine
inhale 5ml of 2% lidocaine by nebulization
saline
control group
Saline
inhale 5ml of saline by nebulization
Interventions
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Lidocaine
inhale 5ml of 2% lidocaine by nebulization
Saline
inhale 5ml of saline by nebulization
Eligibility Criteria
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Inclusion Criteria
2. participants undergoing double-lumen endotracheal intubation under general anesthesia
3. signed informed consent and volunteered to participate in the experiment
Exclusion Criteria
2. preoperative arrhythmia
3. severe coronary artery or heart valve disease
4. sequelae of cerebrovascular accident
5. severe lung, liver, kidney and immune system diseases
6. Suspected difficult airway
7. confirmed or suspected allergy to this trial drug
8. As judged by the investigator to be ineligible for the study, such as communication impairment (language or intelligence)
18 Years
65 Years
ALL
No
Sponsors
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RenJi Hospital
OTHER
Responsible Party
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zhuhao
attending physician
Central Contacts
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Other Identifiers
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IIT-2022-0250
Identifier Type: -
Identifier Source: org_study_id
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