The Influence of Lidocaine Volume on Discomfort During Administration of Local Anesthetic

NCT ID: NCT02086292

Last Updated: 2016-09-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-02-28

Study Completion Date

2014-06-30

Brief Summary

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The aim of the study is to find a simple method for pain reduction that can be used in clinical practice when administering digital nerve block with a single subcutaneous injection. It will be investigated whether a smaller volume of lidocaine can decrease pain during injection.

Detailed Description

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Healthy volunteers will receive a single subcutaneous injection digital nerve block at the base of each ring finger. 2ml 1% lidocaine in one of the fingers, and 1 ml 2% lidocaine in the other. After each injection, the subject will be asked to evaluate the pain on a visual analog scale (0-100 mm). Additionally the sensibility will be tested with a Semmes-Weinstein monofilament, to evaluate if the different methods achieve desired anesthetic effect.

Conditions

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Needlestick Injuries

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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2 milliliter lidocaine

2 ml 1% Lidocaine in one ring finger, 1 ml 2% Lidocaine in the other ring finger

Group Type EXPERIMENTAL

2 ml 1% Lidocaine

Intervention Type PROCEDURE

1 milliliter lidocaine

1 ml 1% Lidocaine in one ring finger, 2 ml 2% Lidocaine in the other ring finger

Group Type EXPERIMENTAL

1 ml 2% Lidocaine

Intervention Type PROCEDURE

Interventions

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2 ml 1% Lidocaine

Intervention Type PROCEDURE

1 ml 2% Lidocaine

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* age 18 - 65

Exclusion Criteria

* regular use of analgesics
* known hypersensitivity of local anaesthetic
* renal-, heart- or liver disease
* known peripheral neuropathy or diabetes mellitus
* local infection on injection site
* circulation disorders in upper extremities (e.g. Raynaud´s phenomenon)
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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St. Olavs Hospital

OTHER

Sponsor Role collaborator

Norwegian University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Vilhjalmur Finsen, prof md

Role: STUDY_DIRECTOR

Norwegian University of Science and Technology

Locations

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Department of neuroscience, NTNU

Trondheim, , Norway

Site Status

Countries

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Norway

References

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Ballo S, Hjelseng T, Tangen LF, Lundbom JS, Skarsvag T, Finsen V. The Influence of Injected Volume on Discomfort During Administration of Digital Block. J Hand Surg Asian Pac Vol. 2016 Oct;21(3):369-73. doi: 10.1142/S2424835516500363.

Reference Type RESULT
PMID: 27595956 (View on PubMed)

Other Identifiers

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2013/2297D

Identifier Type: -

Identifier Source: org_study_id

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