Allopurinol and Quality of Life in Liver Cirrhosis

NCT ID: NCT05828836

Last Updated: 2023-10-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2/PHASE3

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-06-15

Study Completion Date

2023-03-01

Brief Summary

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The study aims to evaluate the impact of allopurinol on patients' related quality of life.

Detailed Description

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Cirrhosis is the late stage of liver damage and possess two phases:. The shift from compensated to decompensated cirrhosis is characterized by the onset of complications) which are associated with substantial morbidity and negative Impact on quality of life (QOL)Cirrhosis and its complications have a substantial economic, social, and personal impact on affected patients, as well as their families and caregivers

Conditions

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Cirrhosis, Liver

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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placebo

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

placebo once daily

allopurinol

Group Type ACTIVE_COMPARATOR

Allopurinol Tablet

Intervention Type DRUG

allopurinol300mg once daily

Interventions

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Allopurinol Tablet

allopurinol300mg once daily

Intervention Type DRUG

Placebo

placebo once daily

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

cirrhosis adult both sex

Exclusion Criteria

* renal insufficiency
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tanta University

OTHER

Sponsor Role lead

Responsible Party

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Khadija Ahmed Mhrose Glal

assistant lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Faculty of Pharmacy

Tanta, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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AqOL

Identifier Type: -

Identifier Source: org_study_id

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