Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
30 participants
INTERVENTIONAL
2016-06-16
2020-12-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
SINGLE
Study Groups
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Arm 1 Ultrasonic
Subjects will receive cleaning of the peri-implant sulcus using ultrasonic instrumentation
Ultrasonic instrumentation
The control treatment consists of supragingival and root debridement using an ultrasonic scaler on low-medium power and coronal polishing with fine grit paste
Arm 2 Glycine
Subjects will receive cleaning of the peri-implant sulcus using glycine powder air-powered debridement
glycine powder air-powered debridement
The intervention treatment consist sof glycine powder air-abrasive debridement (GPAD) using a handheld air polishing device, disposable subgingival nozzle, and glycine powder The nozzle is inserted to the depth of the pocket and all surfaces of the implant (mesial, buccal, distal, lingual) debrided for 5 seconds.
Interventions
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glycine powder air-powered debridement
The intervention treatment consist sof glycine powder air-abrasive debridement (GPAD) using a handheld air polishing device, disposable subgingival nozzle, and glycine powder The nozzle is inserted to the depth of the pocket and all surfaces of the implant (mesial, buccal, distal, lingual) debrided for 5 seconds.
Ultrasonic instrumentation
The control treatment consists of supragingival and root debridement using an ultrasonic scaler on low-medium power and coronal polishing with fine grit paste
Eligibility Criteria
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Inclusion Criteria
* Must have \>1 tooth-borne, non-splinted single dental implant
* Signs of healthy dental implants (pocket probing depth \<4mm and a lack of bleeding upon probing at peri-implant site) OR
* Signs of peri-implant mucositis (\> 4mm probing pocket depths at the dental implant site, bleeding upon probing at \>1 peri-implant site, pre-brushing plaque score of \> 1.9 (modified Plaque Index (mPI)), and radiographic evidence of bone loss less than 2mm).
Exclusion Criteria
* Pregnant or lactating females
* Untreated periodontal conditions
* Use of antibiotics in the past 3 months
* Subjects treated with medication for \>2 weeks with known effects to the oral tissues (i.e. coumadin, phenytoin, nifedipine, cyclosporine, non-steroidal anti-inflammatory drugs)
* Signs of peri-implantitis (pocket probing depth of 4-6mm with bleeding upon probing at \>1 peri-implant site AND radiographic bone loss)
* Dental implant mobility
21 Years
ALL
Yes
Sponsors
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Ohio State University
OTHER
Responsible Party
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Principal Investigators
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Purnima S Kumar, DDS, PhD
Role: PRINCIPAL_INVESTIGATOR
Ohio State University
Locations
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College of Dentistry
Columbus, Ohio, United States
Countries
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References
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Partido B, Saraswat S, Kumar PS. Impact of Glycine Powder Air-Abrasive Debridement on Peri-Implant Mucositis: A Randomized Control Trial of Clinical, Microbial, and Immunological Changes. Clin Oral Implants Res. 2025 Jan;36(1):82-91. doi: 10.1111/clr.14361. Epub 2024 Sep 28.
Other Identifiers
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2016H0397
Identifier Type: -
Identifier Source: org_study_id
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