PET-CT-based Study of Central Mechanisms of Cortical Metabolism in 18F-FDG and 18F-AV1451 Age-related Deafness
NCT ID: NCT05796011
Last Updated: 2023-04-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
30 participants
OBSERVATIONAL
2022-07-06
2024-01-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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Age-related hearing loss patients with hearing aid(s)
Age-related hearing loss patients who were fitted with at least one hearing aid.
hearing aids
Hearing aid(s) fitted for one or two sides of ear.
Age-related hearing loss patients without an hearing aid
Age-related hearing loss patients who were treated without hearing intervention.
without hearing intervention
neither earing aids nor other heaing treatment were applied.
Elderly healthy control
healthy elderly with normal hearing tested by pure tone audiometry.
healthy control
healthy control
Interventions
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hearing aids
Hearing aid(s) fitted for one or two sides of ear.
without hearing intervention
neither earing aids nor other heaing treatment were applied.
healthy control
healthy control
Eligibility Criteria
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Inclusion Criteria
* Normal control group: normal hearing, no MCI, i.e. mean air conduction hearing threshold (0.5, 1, 2, 4 kHz) \< 25 dB HL, no air-bone conduction difference, MMSE score of 27-30; MoCA (corrected for educational attainment) score of 26-30;
* Elderly deafness without hearing aid group: patients diagnosed with elderly deafness, i.e. as a symmetrical, slowly progressive, binaural occurrence with age. hearing loss and reduced speech recognition with predominantly high frequency hearing involvement in the first place, with reference to the Expert Consensus on the Diagnosis and Intervention of Hearing Loss in the Elderly 2019 edition, mean air conduction threshold (PTA) \> 25 dB HL, mean air conduction hearing threshold at high frequency (HF-PTA) \> 25 dB HL, no poor air bone conduction, and no previous hearing aid use.
* No major neurological disorders, serious systemic diseases, family history of genetic predisposition, major psychological disorders.
Exclusion Criteria
* Excluding diseases such as noise deafness and drug-induced deafness.
* Basic information is incomplete.
50 Years
85 Years
ALL
Yes
Sponsors
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Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
OTHER
Responsible Party
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Locations
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Sun Yat-sen Memorial Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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SYSKY-2022-139-01
Identifier Type: -
Identifier Source: org_study_id
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