Role of Surgery in Management of Pineal Region Tumors in Children

NCT ID: NCT05781984

Last Updated: 2023-03-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

25 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-04-30

Study Completion Date

2024-01-31

Brief Summary

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The aim of this observational study is to learn about the role of surgery with its different approaches and modalities in the management of pineal region tumors in pediatric population.the main question it aims to answer is : How can surgery affect the outcome in children with pineal region tumors ?

Detailed Description

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Conditions

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Brain Tumor

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Interventions

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Microsugical Excsosion

Microsurgical excision of pineal region tumor or endoscopic biopsy

Intervention Type PROCEDURE

Other Intervention Names

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Endoscopic Biopsy

Eligibility Criteria

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Inclusion Criteria

* All patients with pineal region tumors with age less than or equal to 18 years old and fit for surgical intervention

Exclusion Criteria

* patients with pineal region tumors older than 18 years old
* and pediatric patients younger than 18 years ild and unfit for surgical intervention
Minimum Eligible Age

2 Months

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Mohamed Ahmed Ibrahim Alghriany

Assistan lecturer of Neurosurgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Mohamed Ahmed Alghriany, Master degree in Neurosurgery

Role: CONTACT

+201009252897

Roshdy Abdelaziz Elkhayat, MD, Professor of Neurosurgery

Role: CONTACT

+201223486390

References

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Choudhry O, Gupta G, Prestigiacomo CJ. On the surgery of the seat of the soul: the pineal gland and the history of its surgical approaches. Neurosurg Clin N Am. 2011 Jul;22(3):321-33, vii. doi: 10.1016/j.nec.2011.04.001.

Reference Type BACKGROUND
PMID: 21801980 (View on PubMed)

Li Y, Zhao G, Wang H, Zhu W, Qu L, Li Y, Yu J. Use of 3D-computed tomography angiography for planning the surgical removal of pineal region meningiomas using Poppen's approach: a report of ten cases and a literature review. World J Surg Oncol. 2011 Jun 15;9:64. doi: 10.1186/1477-7819-9-64.

Reference Type BACKGROUND
PMID: 21676231 (View on PubMed)

Blakeley JO, Grossman SA. Management of pineal region tumors. Curr Treat Options Oncol. 2006 Nov;7(6):505-16. doi: 10.1007/s11864-006-0025-6.

Reference Type BACKGROUND
PMID: 17032562 (View on PubMed)

Mottolese C, Szathmari A, Beuriat PA. Incidence of pineal tumours. A review of the literature. Neurochirurgie. 2015 Apr-Jun;61(2-3):65-9. doi: 10.1016/j.neuchi.2014.01.005. Epub 2014 Aug 10.

Reference Type BACKGROUND
PMID: 25113513 (View on PubMed)

Mori Y, Kobayashi T, Hasegawa T, Yoshida K, Kida Y. Stereotactic radiosurgery for pineal and related tumors. Prog Neurol Surg. 2009;23:106-118. doi: 10.1159/000210057. Epub 2009 Mar 23.

Reference Type BACKGROUND
PMID: 19329865 (View on PubMed)

Wang P, Mao Q, Wang W, Zhou LX, Liu YH. Gamma knife surgery for pineal region tumors: an alternative strategy for negative pathology. Arq Neuropsiquiatr. 2014 Feb;72(2):129-35. doi: 10.1590/0004-282X20130217.

Reference Type BACKGROUND
PMID: 24604367 (View on PubMed)

Behari S, Garg P, Jaiswal S, Nair A, Naval R, Jaiswal AK. Major surgical approaches to the posterior third ventricular region: A pictorial review. J Pediatr Neurosci. 2010 Jul;5(2):97-101. doi: 10.4103/1817-1745.76093. No abstract available.

Reference Type BACKGROUND
PMID: 21559151 (View on PubMed)

Poppen JL. The right occipital approach to a pinealoma. J Neurosurg. 1966 Dec;25(6):706-10. doi: 10.3171/jns.1966.25.6.0706. No abstract available.

Reference Type BACKGROUND
PMID: 5925731 (View on PubMed)

Dandy WE. EXTIRPATION OF THE PINEAL BODY. J Exp Med. 1915 Aug 1;22(2):237-46. doi: 10.1084/jem.22.2.237.

Reference Type BACKGROUND
PMID: 19867913 (View on PubMed)

Morgenstern PF, Souweidane MM. Pineal region tumors: simultaneous endoscopic third ventriculostomy and tumor biopsy. World Neurosurg. 2013 Feb;79(2 Suppl):S18.e9-13. doi: 10.1016/j.wneu.2012.02.020. Epub 2012 Feb 10.

Reference Type BACKGROUND
PMID: 22381843 (View on PubMed)

Masina R, Ansaripour A, Benes V, Berhouma M, Choque-Velasquez J, Eide PK, Fedorko S, Fleck S, Hernesniemi J, Koziarski A, Majovsky M, Podgorski A, Schroeder H, Teo C, Unterberg AW, Yeung JT, Kolias A, Santarius T. Surgical treatment of symptomatic pineal cysts without hydrocephalus-meta-analysis of the published literature. Acta Neurochir (Wien). 2022 Jan;164(1):61-77. doi: 10.1007/s00701-021-05054-0. Epub 2021 Dec 2.

Reference Type BACKGROUND
PMID: 34854993 (View on PubMed)

Other Identifiers

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Pineal Region Tumors

Identifier Type: -

Identifier Source: org_study_id

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