Neurobehavioral Outcomes and Quality of Life in Pediatric Patients With Brain or Head/Neck Tumors Receiving Proton or Photon Radiotherapy
NCT ID: NCT02608762
Last Updated: 2023-05-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
72 participants
OBSERVATIONAL
2013-09-01
2023-12-31
Brief Summary
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Methods: A total of 72 pediatric/adolescent patients, who are diagnosed with brain tumors or head/neck cancers, were prospectively recruited. Neurobehavioral functions will be evaluated using a neuropsychological battery, which includes general cognitive functions, intelligence, memory, executive functions, information processing and emotional/behavioral expressions. The QoL will be evaluated by the health-related QoL questionnaire. All participants will be examined at six phases, which include pre-treatment, 1-month post-treatment, 4-month post-treatment, 1-year post-treatment, 2-year post-treatment and 3-year post-treatment.
Expected results: Patients'neurobehavioral functions and QoL will show significant improvement after treatment, and the improvement will not be diminished across each post-treatment phase.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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pediatric/adolescent patients with brain tumors
A prospectively recruited of newly-diagnosed pediatric/adolescent patients with brain tumors or head/neck cancers
standard adjuvant local radiation therapy or cranial radiation therapy
Interventions
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standard adjuvant local radiation therapy or cranial radiation therapy
Eligibility Criteria
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Inclusion Criteria
* Patients should be considered indicated for receiving the subsequent course of local radiotherapy
Exclusion Criteria
* Patients have visual and/or hearing impairments which obviously impede the administration of neurocognitive assessment
* Patients cannot underwent brain MRI examination because of clinical contraindications, such as renal insufficiency (GFR \<30)
1 Month
18 Years
ALL
No
Sponsors
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Chang Gung Memorial Hospital
OTHER
Responsible Party
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Locations
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Chang Gung Memorial Hospital
Taoyuan District, , Taiwan
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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102-5729A3
Identifier Type: -
Identifier Source: org_study_id
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