Effect of Dexmedetomidine on Left Ventricular Function in Coronary Artery Bypass Graft Surgery Outcome
NCT ID: NCT05778305
Last Updated: 2024-10-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
EARLY_PHASE1
50 participants
INTERVENTIONAL
2023-01-29
2023-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Dexmedetomidine in Off Pump Coronary Artery Bypass Grafting
NCT05577871
Effect Of Dexmedetomidine On Sublingual Microcirculation In Patients Undergoing On Pump CABG Surgery
NCT02714725
Dexmedetomidine vs Control on Attenuation Hemodynamic Response to Noxious Stimuli in CABG Surgical Patients
NCT06238011
Perioperative Dexmedetomidine and 30-Day Outcomes After Adult Cardiac Surgery
NCT07249164
The Effects of Dexmedetomidine on Microcirculation and Surgical Outcomes After Cardiac Surgeries
NCT02786212
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Incidence of intraoperative and post operative ischemia and arrhythmias using Electrocardiogram (ECG) as well as the length of ICU and hospital stay.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
TRIPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Dexmedetomidine group
patients will have loading Dexmedetomidine( 1ug/kg) over 10 minutes followed by continuous infusion of (0.5ug/kg/hr) from the initiation of anaesthesia up to extubation in the ICU. Patients will not be extubated until completely awake and have no sign of arrhythmias and bleeding
Dexmedetomidine
a central sympatholytic drug
control group
patients will receive the same volume of 0.9% saline infusion as loading and maintenance infusion.
normal saline
saline is given to control group
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Dexmedetomidine
a central sympatholytic drug
normal saline
saline is given to control group
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
* Dementia patients
* Poor ventricular function with ejection fraction below 40%
* Asthmatic patients
* Uncontrolled diabetic patients with HbA1c above 8
* Combined surgeries (CABG+ valves)
* Emergency surgeries.
* Pre-existing arrhythmia
* Patients with renal impairment
* Patients with hepatic impairment
* Patients with heart block
* Off-pump CABG
30 Years
60 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Ain Shams University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Rania Maher Hussien, MD
Associate professor of Anesthesia
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Ain Shams University
Cairo, Abassia, Egypt
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
FMASU MD283/2022
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.