Study of Speech Function in Epileptic Patients Based on Stereoelectroencephalography Signal

NCT ID: NCT05776745

Last Updated: 2023-03-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

5 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-03-20

Study Completion Date

2023-12-25

Brief Summary

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Based on stereoelectroencephalography model in the treatment of epilepsy patients, this study conducted language-related experimental studies without interfering with normal monitoring treatment. Meanwhile, voice data and intracranial electrophysiological data were collected for analysis. To study the mechanism related to the language function of patients, try to establish a model to decode the intracranial electrophysiological data related to language.

Detailed Description

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Conditions

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Epilepsy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Epileptic

Epileptic with stereoelectroencephalography

Group Type EXPERIMENTAL

Speech

Intervention Type BEHAVIORAL

Patients read specific words and sentences

Stereoelectroencephalography

Intervention Type DEVICE

Using stereoelectroencephalography to record the Intracranial EEG of the patient

Interventions

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Speech

Patients read specific words and sentences

Intervention Type BEHAVIORAL

Stereoelectroencephalography

Using stereoelectroencephalography to record the Intracranial EEG of the patient

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients with focal refractory epilepsy also need preoperative evaluation with SEEG

Exclusion Criteria

* History of major depression or psychiatric disorders and medication that causes symptoms of psychiatric disorders
* Patients with severe cognitive impairment (MMSE score ≤15), unable to complete the language function test
Minimum Eligible Age

16 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

Sponsor Role lead

Responsible Party

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Hemmings Wu

Neurosurgeon, Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Zhejiang University School of Medicine Second Affiliated Hospital

Hangzhou, Zhejiang, China

Site Status

Countries

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China

Other Identifiers

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2022-0113

Identifier Type: -

Identifier Source: org_study_id

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