Prevention of Post-Operative Nausea and Vomiting With Propofol Infusion
NCT ID: NCT05759481
Last Updated: 2025-04-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
68 participants
INTERVENTIONAL
2024-02-01
2025-03-12
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Propofol
Low-dose propofol infusion at 25 mcg/kg/min
Propofol
Propofol is administered starting at surgery induction and ending at skin closure
Placebo
Same volume of 0.9% normal saline as the study group
Placebo
Placebo is administered starting at surgery induction and ending at skin closure
Interventions
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Propofol
Propofol is administered starting at surgery induction and ending at skin closure
Placebo
Placebo is administered starting at surgery induction and ending at skin closure
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
2. Documented history of Patient's self-disclosure of PONV and/or motion sickness during pre-anesthesia discussions
3. No documented allergy/adverse reaction to propofol
4. English speaking
5. At least 18 years of age
Exclusion Criteria
2. Unable to provide consent independently
3. Allergy or adverse reaction to propofol
4. Emergency surgery
18 Years
ALL
No
Sponsors
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Milton S. Hershey Medical Center
OTHER
Responsible Party
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Sonal Sharma
Assistant Professor, Department of Anesthesiology and Perioperative Medicine
Principal Investigators
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Sonal Sharma, MD
Role: PRINCIPAL_INVESTIGATOR
Assistant Professor, Department of Anesthesiology and Perioperative Medicine
Locations
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Penn State Health Milton S Hershey Medical Center
Hershey, Pennsylvania, United States
Countries
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Other Identifiers
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STUDY00021935
Identifier Type: -
Identifier Source: org_study_id
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