Heart Rate Variability and Postoperative Nausea Vomiting

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-10-17

Study Completion Date

2021-12-31

Brief Summary

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Propofol and sevoflurane have different effects on heart rate variability. It has not yet been reported whether this difference in effect remains at recovery time after anesthesia and the difference is related to postoperative nausea and vomiting has not been studied. The aim of this study is observe whether propofol and sevoflurane have different effects on heart rate variability during recovery and the differences can predict the occurrence of postoperative nausea and vomiting.

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Detailed Description

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Different types of anesthetics have different effects on heart rate variability. However It has not yet been reported whether this difference in effect remains at recovery time after anesthesia.

Several studies have been reported that preoperative heart rate variability predicted the occurence of postoperative nausea and vomiting. However, whether the difference in heart rate variability after anesthesia is related to the difference in postoperative nausea and vomiting has not been studied. Therefore, this study aims to observe whether propofol and sevoflurane have differences during recovery period after anesthesia in heart rate variabiliy. In addition, we want to examine that these differences during recovery period in heart rate variability can predict the occurrence of nausea and vomiting within 24 hours after surgery.

Conditions

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Postoperative Nausea and Vomiting

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Propofol

General anesthesia using propofol infusion

Propofol

Intervention Type DRUG

General anesthesia using propofol infusion

Sevoflurane

General anesthesia using sevoflurane

Sevoflurane

Intervention Type DRUG

General anesthesia using sevoflurane

Interventions

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Propofol

General anesthesia using propofol infusion

Intervention Type DRUG

Sevoflurane

General anesthesia using sevoflurane

Intervention Type DRUG

Other Intervention Names

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Propofol infusion Sevoflurane inhalation

Eligibility Criteria

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Inclusion Criteria

* Scheduled breast surgery under general anesthesia

Exclusion Criteria

* Arrhythmia
* Uncooperative with the measuring heart rate variability
* Diabetes
* Hypertension on medication
* Patients taking psychiatric drugs
* Thyroid disease

Minimum Eligible Age

20 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No