Risk Factors for Postoperative Nausea/Vomiting

NCT ID: NCT02944942

Last Updated: 2017-03-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-09-30

Study Completion Date

2017-02-28

Brief Summary

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General anesthetic technique plays a key role in most surgical procedures. This technique has some complications especially postoperative nausea/vomiting (PONV). This complication can lead to serious problems. Department of Anesthesiology has developed and implemented a PONV prophylaxis guideline for high risk PONV patients but PONV still remains.

Detailed Description

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Objective: To identify risk factors for PONV after implementation of PONV prophylaxis guideline.

Methods: This will be a retrospective analytic study. Relevant clinical data from medical records of adult patients undergoing general anesthesia in Srinagarind Hospital from November 2014 to February 2015 will be used to identify relevant risk factors.

Conditions

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Postoperative Nausea and Vomiting

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Postoperative nausea and vomiting

Group 1: Patients undergoing general anesthesia with postoperative nausea and vomiting Group 2: Patients undergoing general anesthesia without postoperative nausea and vomiting

General anesthesia

Intervention Type PROCEDURE

Patients undergoing general anesthesia

Interventions

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General anesthesia

Patients undergoing general anesthesia

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* ASA classification I-III

Exclusion Criteria

* Incomplete or illegible medical records
* Patients who underwent cardio-thoracic surgery
* Patient who had chronic treatment with antiemetic drugs
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Khon Kaen University

OTHER

Sponsor Role lead

Responsible Party

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Thepakorn Sathitkarnmanee

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sirirat Tribuddharat, MD

Role: PRINCIPAL_INVESTIGATOR

Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

Locations

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Srinagarind Hospital, Faculty of Medicine, Khon Kaen University

Khon Kaen, Changwat Khon Kaen, Thailand

Site Status

Countries

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Thailand

References

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Apfel CC, Laara E, Koivuranta M, Greim CA, Roewer N. A simplified risk score for predicting postoperative nausea and vomiting: conclusions from cross-validations between two centers. Anesthesiology. 1999 Sep;91(3):693-700. doi: 10.1097/00000542-199909000-00022.

Reference Type RESULT
PMID: 10485781 (View on PubMed)

Blanc VF, Ruest P, Milot J, Jacob JL, Tang A. Antiemetic prophylaxis with promethazine or droperidol in paediatric outpatient strabismus surgery. Can J Anaesth. 1991 Jan;38(1):54-60. doi: 10.1007/BF03009164.

Reference Type RESULT
PMID: 1989740 (View on PubMed)

Chatterjee S, Rudra A, Sengupta S. Current concepts in the management of postoperative nausea and vomiting. Anesthesiol Res Pract. 2011;2011:748031. doi: 10.1155/2011/748031. Epub 2011 Nov 3.

Reference Type RESULT
PMID: 22110499 (View on PubMed)

Doubravska L, Dostalova K, Fritscherova S, Zapletalova J, Adamus M. Incidence of postoperative nausea and vomiting in patients at a university hospital. Where are we today? Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2010 Mar;154(1):69-76. doi: 10.5507/bp.2010.012.

Reference Type RESULT
PMID: 20445713 (View on PubMed)

Jokinen J, Smith AF, Roewer N, Eberhart LH, Kranke P. Management of postoperative nausea and vomiting: how to deal with refractory PONV. Anesthesiol Clin. 2012 Sep;30(3):481-93. doi: 10.1016/j.anclin.2012.07.003. Epub 2012 Aug 14.

Reference Type RESULT
PMID: 22989590 (View on PubMed)

Other Identifiers

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HE571413

Identifier Type: -

Identifier Source: org_study_id

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