the Effect of Three Different Analgesic Techniques on the Incidence of Postoperative Nausea and Vomiting
NCT ID: NCT03313479
Last Updated: 2017-10-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
75 participants
OBSERVATIONAL
2017-10-30
2018-01-01
Brief Summary
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Detailed Description
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The incidence of PONV after general anesthesia is about 30% in all post-surgical patients but up to 80% in high-risk patients despite advances in anesthetics and anesthesia techniques.
Despite new antiemetic drugs the overall incidences remain high especially in subjects with increased patient-related risk-factors such as in female gender, non-smoking status, a history of motion sickness or previous PONV, inhalational anesthetics, certain types of surgery, and opioid use. Scleral buckling (SB) which is still thought to be the most efficacious and cost-effective primary procedure for the treatment of uncomplicated retinal detachment is often associated with postoperative pain as well as nausea and vomiting. Preoperative injections of local anesthetics via retrobulbar, peribulbar, or subtenon routes in patients undergoing vitreoretinal surgery under general anesthesia (GA) have been reported to reduce postoperative pain, nausea, and vomiting.
Topical lidocaine drops have also has been used intraoperatively to decrease the incidence and severity of the OCR and to prevent pain and PONV after strabismus surgery and vitrectomy without scleral buckling .
The current study was designed to compare the effect of three different analgesic techniques ; IV analgesia , peribulbar block and topical xylocaine jel on the incidence of ponv after scleral buckling under general anesthesia.
Conditions
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Keywords
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Group 1
GA and Dexmedetomidine
Dexmedetomidine
Dexmedetomidine will be given with GS
group 2
GA and peribulbar
No interventions assigned to this group
group3
GA and xylocaine gel
No interventions assigned to this group
Interventions
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Dexmedetomidine
Dexmedetomidine will be given with GS
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* aged between 18-80 years
* ASA physical status Ι\&II -indicated for repair of retinal detachment with scleral buckling. -
Exclusion Criteria
* coagulation defects or receiving anticoagulants
* hypersensitivity to the used drugs
* history of motion sickness or PONV
* diabetes mellitus
* gastrointestinal disease
* smokers
* menstruating ladies
* ASA status more than II
18 Years
80 Years
ALL
No
Sponsors
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Cairo University
OTHER
Responsible Party
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Hassan Mohamed Ali
lecturer of anesthesia
Locations
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Cairo University
Cairo, Giza Governorate, Egypt
Countries
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Central Contacts
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Facility Contacts
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HASSAN M ALI, LECTURER
Role: primary
Other Identifiers
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badawy 1
Identifier Type: -
Identifier Source: org_study_id