Assessment of the Effect of Non-surgical Periodontal Treatment on Endothelial Function- a Prospective Study
NCT ID: NCT05691426
Last Updated: 2023-01-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
UNKNOWN
40 participants
OBSERVATIONAL
2022-10-01
2024-06-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Peri-implantitis and Peri-implant Mucositis
NCT05906810
Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Periodontitis.
NCT05906797
Effects of Non-surgical Periodontal Therapy on Cardiovascular Risk
NCT05459727
Effect of Nonsurgical Periodontal Therapy on Salivary Biomarkers Related to Bone Turnover in Smoker and Nonsmoker Periodontitis Patients
NCT06270004
Effect of Non Surgical Periodontal Therapy on Inflammatory Markers in Chronic Periodontitis Patients
NCT05295576
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
CASE_CONTROL
PROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Test
Periodontitis patients
Assessment of pulse wave amplitude (PWA)
Assessment of pulse wave amplitude (PWA) through peripheral arterial tonometry (PAT) using the device EndoPAT (Itamar Medical)
Salivary Nitric Oxide
assessment the levels of salivary Nitric Oxide using a Nitric Oxide colorimetric detection kit,
Control
Periodontally healthy patients
Assessment of pulse wave amplitude (PWA)
Assessment of pulse wave amplitude (PWA) through peripheral arterial tonometry (PAT) using the device EndoPAT (Itamar Medical)
Salivary Nitric Oxide
assessment the levels of salivary Nitric Oxide using a Nitric Oxide colorimetric detection kit,
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Assessment of pulse wave amplitude (PWA)
Assessment of pulse wave amplitude (PWA) through peripheral arterial tonometry (PAT) using the device EndoPAT (Itamar Medical)
Salivary Nitric Oxide
assessment the levels of salivary Nitric Oxide using a Nitric Oxide colorimetric detection kit,
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Group 2: patients with periodontitis stage III or IV and grades A,B or C.
Exclusion Criteria
* Heavy smokers(\>10 cigarettes per day),
* Regular administration of drugs resulting in gingival hyperplasia,root planning in the past 6 months
* Regular administration of drugs resulting in gingival hyperplasia (such as cyclosporine and phenytoin)
* Recent antibiotic use (in the past 3 months)
* Non-surgical periodontal therapy in the past 6 monthsp
18 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Sharjah
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Zahi BADRAN
Professor
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Zahi Badran
Role: STUDY_DIRECTOR
University of Sharjah
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
University Dental Hospital Sharjah
Sharjah city, , United Arab Emirates
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
REC-22-02-28-04-S
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.