Specialized Pro-resolving Mediators (SPM) as Biomarkers of Periodontal Inflammation
NCT ID: NCT05706675
Last Updated: 2023-01-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
40 participants
INTERVENTIONAL
2022-10-01
2024-06-30
Brief Summary
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There are alot of research explaining the different types of inflammatory mediators that could be found in periodontitis patients. But there are a few research have been talking about lipoxin A4 as an inflammatory biomarker that could detect the effect of non surgical periodontal therapy effect on the periodontal health.
And the aim of the study is to assess the effect of this non surgical periodontal therapy on the periodontal health by assessing the concentration of this biomarker.
Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
DIAGNOSTIC
NONE
Study Groups
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Experimental
Periodontitis patients that will be treatyed with Non surgical Periodontal Therapy
Non surgical periodontal therapy
Manual root planning+Ultrasonic subgingival debridement
Control
Periodontally healthy patients
No interventions assigned to this group
Interventions
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Non surgical periodontal therapy
Manual root planning+Ultrasonic subgingival debridement
Eligibility Criteria
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Inclusion Criteria
* Test group:
* Patients diagnosed with generalized periodontitis (Stage 3/4, Grade a,b or c).
* Having at least 15 remaining teeth.
* Mentally able to understand the communication and to express an informed consent
Exclusion Criteria
* Antibiotics/Anti-inflammatory drugs taken in the last month
* Women with suspected/known pregnancy, or taking any hormone-based treatment
* Patients suffering from Xerostomia.
* Patients smoking more than 20 cig/day.
* Previous periodontal therapy in the last 3-6 months
20 Years
60 Years
ALL
Yes
Sponsors
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University of Sharjah
OTHER
Responsible Party
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Zahi BADRAN
Professor
Principal Investigators
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Prof. Zahi Badran, Phd
Role: STUDY_DIRECTOR
University of Sharjah
Locations
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University Dental Hospital Sharjah
Sharjah city, , United Arab Emirates
Countries
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Central Contacts
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Facility Contacts
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Zahi BADRAN
Role: primary
Other Identifiers
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REC-22-02-28-02-S
Identifier Type: -
Identifier Source: org_study_id