Trunk Oriented Exercises Versus Whole-body Vibration for Duchenne Muscular Dystrophy

NCT ID: NCT05688072

Last Updated: 2023-04-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-15

Study Completion Date

2023-04-15

Brief Summary

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The abdominal muscles play an important role in stabilizing the trunk and providing postural stability. Children with Duchene muscular dystrophy have weak muscles, which may impair postural adjustments. These postural adjustments are required for gait and dynamic balance during the daily living activities.

Detailed Description

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Conditions

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Muscular Dystrophy, Duchenne Type

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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study group (A)

Group Type ACTIVE_COMPARATOR

trunk oriented exercise

Intervention Type OTHER

trunk oriented exercises include: stretching exercises, stabilization exercises (active or active-assisted), arm exercises in fixed trunk position, trunk-oriented exercises (active or active-assisted), trunk mobilization (sitting and lying position), and functional reaching exercises with different ranges of motion in shoulder elevation

Study group (B)

Group Type ACTIVE_COMPARATOR

whole body vibration

Intervention Type OTHER

WBV application technique. The children assume a full squatting position on a vibration platform. The apparatus will set at a frequency of 30 Hz, an amplitude of 2 mm, and a duration of 5 min. The children were instructed to remain in squatting position after the vibration started and to report any discomfort that arose. At the end of 5 min, the vibration turned off automatically. Thereafter, the children rested for 1 min. They were then asked to stand on the vibration platform while supported by the therapist for 5 min, with the same parameters as those used in the squatting position. The total time of application of WBV in each session was 10 min.

Interventions

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trunk oriented exercise

trunk oriented exercises include: stretching exercises, stabilization exercises (active or active-assisted), arm exercises in fixed trunk position, trunk-oriented exercises (active or active-assisted), trunk mobilization (sitting and lying position), and functional reaching exercises with different ranges of motion in shoulder elevation

Intervention Type OTHER

whole body vibration

WBV application technique. The children assume a full squatting position on a vibration platform. The apparatus will set at a frequency of 30 Hz, an amplitude of 2 mm, and a duration of 5 min. The children were instructed to remain in squatting position after the vibration started and to report any discomfort that arose. At the end of 5 min, the vibration turned off automatically. Thereafter, the children rested for 1 min. They were then asked to stand on the vibration platform while supported by the therapist for 5 min, with the same parameters as those used in the squatting position. The total time of application of WBV in each session was 10 min.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* diagnosed as Duchenne muscular dystrophy,
* aged from 6 to 10 years,
* having grade 3+ muscle strength in lower limbs and trunk muscles.
* had functional range of motion for upper and lower limb joints,
* able to walk alone level I and II of Ambulation function classification system for DMD (AFCSD)

Exclusion Criteria

* congenital or acquired skeletal deformities or cardiopulmonary dysfunction,
* had undergone previous orthopedic surgery in lower limbs,
* had abnormal motor development or neurological disease that affect balance
* and gait, and
* behavioral problems causing inability to cooperate during the study.
Minimum Eligible Age

6 Years

Maximum Eligible Age

10 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Marwa Shafiek Mustafa Saleh

assistance professor doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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marwa S saleh

Giza, , Egypt

Site Status

Countries

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Egypt

References

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Ali MS, Saleh MS. Trunk-oriented Exercises Versus Whole-body Vibration on Abdominal Thickness and Balance in Children with Duchene Muscular Dystrophy. J Musculoskelet Neuronal Interact. 2024 Mar 1;24(1):47-54.

Reference Type DERIVED
PMID: 38427368 (View on PubMed)

Other Identifiers

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Treatment of Duchenne syndrome

Identifier Type: -

Identifier Source: org_study_id

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