Interest of Molecular Analysis of Cerebral Thrombi in Determining the Prognosis and Etiology of Cerebral Infarction

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

311 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-02-08

Study Completion Date

2025-02-28

Brief Summary

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The MATISSE (Molecular Analysis of Thrombus for Ischemic Stroke prognosis and Etiology) project evaluates the hypothesis that the molecular composition of cerebral thrombus in metabolites, lipids, and proteins conditions the clinical prognosis at 3 months of the infarction and informs on its etiological subtype

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Detailed Description

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Conditions

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Ischemic Stroke

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patient suffering from ischemic stroke

Thrombi and blood analyses

Intervention Type OTHER

Thrombi and blood will be collected during thrombectomy

Interventions

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Thrombi and blood analyses

Thrombi and blood will be collected during thrombectomy

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Male or female 18 years of age or older;
* Patient with a cerebral infarction documented by brain imaging who received endovascular treatment by mechanical thrombectomy;
* Patient for whom it was possible to collect cerebral thrombus for LC-MS analysis during mechanical thrombectomy:
* Patient who was informed of the study and formulated a non-opposition to participation. If not, patient for whom a relative was informed and formulated a non-opposition.

Exclusion Criteria

* Patient with a cerebral infarction documented by cerebral imaging, having benefited from an endovascular treatment with mechanical thrombectomy that did not allow the extraction of a cerebral thrombus.
* Protected persons (articles L1121-5, L1121-6 and L121-8 of the Public Health Code): pregnant or breast-feeding women, persons deprived of liberty, under guardianship or curatorship

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No