Brain MRI in Stroke Patients With Intracardiac Thrombus

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

122 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-05-01

Study Completion Date

2020-12-31

Brief Summary

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Acute infarction patterns have been described in cardioembolic stroke, mainly with atrial fibrillation (AF) or patent foramen ovale. We aimed to analyse acute infarction MRI characteristics in stroke patients with intracardiac thrombus (ICT) compared with stroke patients with AF.

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Detailed Description

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Conditions

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Stroke Intracardiac Thrombus

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Atrial fibrillation

stroke patients with atrial fibrillation

No intervention,

Intervention Type OTHER

pure observational study

Intracardiac thrombus

stroke patients with intracardiac thrombus

No intervention,

Intervention Type OTHER

pure observational study

Interventions

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No intervention,

pure observational study

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* consecutive patients presenting with acute symptomatic cardioembolic infarction associated with ICT, recruited and registered in the stroke database between June 2018 and November 2019 of our centre (Nîmes University Hospital, France). These patients were compared with consecutive cardioembolic stroke patients with known or newly discovered AF (in the absence of ICT on echocardiography), recruited during the same time period.
* Brain MRI (including diffusion-weighted imaging \[DWI\]) performed within one week of symptom onset; complete etiological work-up including intracranial (time-of-flight \[TOF\], gadolinium-enhanced magnetic resonance angiography \[MRA\], or computed tomographic angiography \[CTA\]) and extracranial (gadolinium-enhanced MRA, CTA, or duplex ultrasound) vessel imaging; transthoracic or transoesophageal echocardiography; and ≥24h ECG monitoring (acute stroke unit monitoring and/or Holter ECG monitoring).