Red Cell Distribution Width,,NT-proBNP and cTnT in Acute Myocardial Infraction Patient
NCT ID: NCT05595278
Last Updated: 2022-11-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
30 participants
OBSERVATIONAL
2022-11-13
2023-07-13
Brief Summary
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Detailed Description
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* Type of study: Observational prospective study
* Place of study: Sohag cardiology and gastroenterology center, department of cardiology and cardiac care unit.
* Ethical considerations: This research will be revised by the Scientific Ethical Committee of Sohag University Hospital. Consents will be taken from all patients.
* Study Methods:
* A prospective study on 30 patients diagnosed as acute myocardial infarction on which measurement of CBC, serum NT-proBNP, and cTnT levels will be performed at the time of admission and by the time of discharge.
* All patients included in the study will be subjected to:
1. Full history:
1. Personal history: e.g. age, sex and smoking.
2. Family history of cardiac diseases
3. Medical history of: Hypertension, Ischemic heart disease, prior coronary artery bypass grafting, Prior Percutaneous coronary intervention, Prior Stroke, Prior Atrial fibrillation, therapeutic history
2. Detailed clinical examination
3. Electrocardiogram
4. Laboratory investigation:
1. Routine investigation in the form of CBC including RDW
2. Specific investigation which include NT-proBNP and cTnT
Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Interventions
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(CBC) ,(NT-proBNP) ,(cTnT)
complete blood count (CBC) including RDW with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) in a cohort of acute myocardial infarction (AMI) patients.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Decompensated heart failure
* Pulmonary hypertention
* Acute pulmonary embolism
* Septic shock
ALL
No
Sponsors
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Sohag University
OTHER
Responsible Party
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Hemat Kamel Maarouf
Resident doctor at clinical and chemical pathology department
Locations
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Sohag University Hospital
Sohag, , Egypt
Countries
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Central Contacts
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Abdelhady R Abdel-Gawad, assistant professor
Role: CONTACT
Facility Contacts
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Magdy M Amin, professor
Role: primary
References
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Nascimento BR, Brant LCC, Marino BCA, Passaglia LG, Ribeiro ALP. Implementing myocardial infarction systems of care in low/middle-income countries. Heart. 2019 Jan;105(1):20-26. doi: 10.1136/heartjnl-2018-313398. Epub 2018 Sep 29.
Barberi C, van den Hondel KE. The use of cardiac troponin T (cTnT) in the postmortem diagnosis of acute myocardial infarction and sudden cardiac death: A systematic review. Forensic Sci Int. 2018 Nov;292:27-38. doi: 10.1016/j.forsciint.2018.09.002. Epub 2018 Sep 17.
Alaour B, Liew F, Kaier TE. Cardiac Troponin - diagnostic problems and impact on cardiovascular disease. Ann Med. 2018 Dec;50(8):655-665. doi: 10.1080/07853890.2018.1530450. Epub 2018 Nov 21.
Other Identifiers
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Soh-Med-2210-05
Identifier Type: -
Identifier Source: org_study_id
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