High Sensitive C-reactive Protein to Albumin Ratio in Acute Coronary Syndrome

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

240 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-11-01

Study Completion Date

2025-10-01

Brief Summary

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assess the use of hs- C-reactive protein to albumin ratio (hs-CAR) in prediction of in-hospital short-term major adverse cardiac events (MACEs) in acute coronary syndrome (ACS) patients

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Detailed Description

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Observational study conducted at coronary care unit(CCU) in sohag university hospital It included patients with ACS diagnosed according to AHA/ACCF guidelines (according to symptoms, ECG findings and serum troponin levels), who had admitted to the CCU.

Venous blood samples were instantly collected on admission to the hospital. hs-CRP , serum albumin level were measured.

hs-CAR is calculated and the patients divided into two groups: Group A ( patients with high hs-CAR) and group B ( patients with low hs-CAR) In-hospital MACE was regarded as the end point of our study. It was defined as acute heart failure, cardiogenic shock, reinfarction, all-cause death, serious arrhythmia and cardiac death

Conditions

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Acute Coronary Syndrome

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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high sensitive c-reactive protein to albumin ratio (hs-CAR)

Group A ( patients with high hs-CAR) and group B ( patients with low hs-CAR)

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* All patients aged 18 Year or older presented by ACS not candidet for primary percutaneus coronary intervention ( PCI ) .

Exclusion Criteria

* • Patients aged \< 18 years old

* Patients who have eGFR \<60 ml/kg /m2
* Patients who have malignancies
* Patients who have chronic heart failure (NYHA class \>II)
* Pateints who have chronic liver disease
* Patients who have nephrotic syndrome
* Patients who have acute cerebrovascular stroke
* Pregnant women
* Patients who have recent infection

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No