Association of Plasma N-terminal Pro-Brain Natriuretic Peptide Levels With the Burden of Coronary Artery Disease

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

800 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-09-01

Study Completion Date

2025-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study aim to investigate the association between plasma NT-proBNP levels and the presence, extent and severity of stenosis in patients with suspected coronary artery disease.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

BNP, Serum Troponin and D-dimer as Risk Factors in Patients With COVID-19

NCT04433026

COVID-19

UNKNOWN

Predictive Value of NT-proBNP on MACEs After Acute Coronary Syndrome

NCT06569511

Acute Coronary Syndrome ST-segment Elevation Myocardial Infarction (STEMI) Non-ST-Segment Elevation Myocardial Infarction (NSTEMI) +1 more

COMPLETED

Diagnostic and Prognostic Role of Troponin and Brain Natriuretic Peptide in Pediatric Patients With Cardiomyopathy in Correlation to Echocardiography Findings

NCT06348732

Cardiomyopathies

NOT_YET_RECRUITING

Management of Cardiovascular Risk Factors

NCT00848380

Cardiovascular Risk Factors Cardiovascular Diseases

COMPLETED

Evaluation of Patients With Known or Suspected Heart Disease

NCT00001313

Peripheral Artery Disease Coronary Disease Diabetes and Heart Failure +4 more

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The investigators prospectively measured plasma NT-proBNP levels in consecutive patients referred to the center for elective diagnostic coronary angiography due to symptoms or signs of coronary artery disease over a two- year period. Patients with conditions known to elevate NT-proBNP levels, including heart failure, severe valvular disease, atrial fibrillation, severe chronic kidney disease (eGFR \< 30 mL/min), prior coronary artery bypass grafting, or age over 80 years, were excluded.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Chronic Coronary Syndrome Chronic Coronary Total Occlusion Coronary Arterial Disease (CAD) Stable Chronic Angina NT-pro-BNP

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

BNP

Measurement of plasma NT-proBNP level.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* patient referred for elective coronary angiography due to suspected CAD.
* NT-proBNP measurement during hospitalization

Exclusion Criteria

* heart failure
* severe valvular disease
* atrial fibrillation
* severe chronic kidney disease (eGFR \< 30 mL/min)
* prior coronary artery bypass grafting
* age over 80 years

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No