The Effect of Antenatal Corticosteroid on Umbilical Artery Doppler Velocimetry in IUGR

NCT ID: NCT05588986

Last Updated: 2023-08-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

149 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-02-02

Study Completion Date

2019-02-02

Brief Summary

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The purpose of this study is to evaluate the effect of antenatal corticosteroid administration on umbilical artery Doppler velocimetry measurements in pregnancies complicated by IUGR.

Detailed Description

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This study was conducted with pregnant women who were likely to have preterm birth and were treated with antenatal corticosteroids. Betamethasone was used as an antenatal corticosteroid. UA Doppler measurements (PI, S/D ratio, RI) before antenatal corticosteroid administration and 24 and 48 hours after the last dose of corticosteroid administration were evaluated in pregnant groups complicated with IUGR and uncomplicated with IUGR and compared with each other.

Conditions

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Intrauterine Growth Restriction

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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with IUGR

Pregnant women who received antenatal corticosteroid therapy and complicated with intrauterine growth retardation

ultrasonography

Intervention Type OTHER

Umbilical artery Doppler evaluation by ultrasonography just before the first dose of antenatal corticosteroid, 24 hours and 48 hours after the last dose.

without IUGR

Pregnant women who received antenatal corticosteroid therapy and were not complicated by intrauterine growth retardation

ultrasonography

Intervention Type OTHER

Umbilical artery Doppler evaluation by ultrasonography just before the first dose of antenatal corticosteroid, 24 hours and 48 hours after the last dose.

Interventions

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ultrasonography

Umbilical artery Doppler evaluation by ultrasonography just before the first dose of antenatal corticosteroid, 24 hours and 48 hours after the last dose.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

pregnant women who were likely to have preterm delivery and were treated with antenatal corticosteroids.

Exclusion Criteria

Pregnant women who had complicated pregnancy with fetal anomaly, who had multiple pregnancies, who left their pregnancy follow-up unfinished, and those under 18 years of age were excluded from the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

49 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Marmara University

OTHER

Sponsor Role collaborator

Merve Demir

OTHER

Sponsor Role lead

Responsible Party

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Merve Demir

Research assistant

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Merve Demir

Kocaeli, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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Antenatal-IUGR

Identifier Type: -

Identifier Source: org_study_id

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