Clinical Features, Outcomes, and Therapeutics of Pregnancy-Related Aortic Dissection

NCT ID: NCT05501145

Last Updated: 2022-09-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

75 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-01-01

Study Completion Date

2022-07-31

Brief Summary

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Aortic dissection in pregnancy represents a lethal risk to both the mother and fetus, it has yet to yield the optimal therapeutic strategy. The aim of this study was to characterize the clinical features and outcomes in women with pregnancy-related acute aortic dissection, and to suggest therapeutic guidelines.

Detailed Description

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Conditions

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Aortic Dissection Pregnancy Related

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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cesarean section and aortic repair

The timing of aortic repair and delivery have to be determined based on the type of the dissection, the stage of pregnancy (the gestation age), and the status of the fetus, as well as the level of local neonatal service.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Women who presented with aortic dissection during pregnancy or post partum ≤12 weeks.

Exclusion Criteria

* Loss of surgical information.
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Beijing Anzhen Hospital

OTHER

Sponsor Role collaborator

Shanghai Zhongshan Hospital

OTHER

Sponsor Role collaborator

Guangdong Provincial People's Hospital

OTHER

Sponsor Role collaborator

Nanjing Medical University

OTHER

Sponsor Role lead

Responsible Party

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Hong Liu

Principal Investigator of Cardiovascular Surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hong-jia Zhang, MD

Role: STUDY_CHAIR

Beijing Anzhen Hospital

Locations

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Beijing Anzhen Hospital

Beijing, , China

Site Status

Department of Obstetrics and Gynecology, Guangdong Provincial People's Hospital

Guangzhou, , China

Site Status

Department of Cardiac Surgery, Affiliated Hospital of Qingdao University

Qingdao, , China

Site Status

Department of Obstetrics and Gynecology, Zhongshan Hospital

Shanghai, , China

Site Status

Countries

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China

References

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Liu H, Yang L, Chen CY, Qian SC, Ma LY, Diao YF, Wu XY, Wu SY, Dong ZQ, Shao YF, Zhang HJ, Sun LZ, Zhu JM, Zhang JR, Li H. Management strategies and outcomes in pregnancy-related acute aortic dissection: a multicentre cohort study in China. Heart. 2024 Oct 28;110(22):1298-1306. doi: 10.1136/heartjnl-2024-324009.

Reference Type DERIVED
PMID: 39266045 (View on PubMed)

Other Identifiers

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5A Plan VII

Identifier Type: -

Identifier Source: org_study_id

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