Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial
NCT ID: NCT05581303
Last Updated: 2025-10-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
PHASE3
7297 participants
INTERVENTIONAL
2022-12-14
2026-12-29
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Placebo
Placebo will be administered by subcutaneous injection
Placebo
Placebo given by subcutaneous injection once every 12 weeks (Q12W).
Olpasiran
Olpasiran will be administered by subcutaneous injection
Olpasiran
Olpasiran given by subcutaneous injection Q12W.
Interventions
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Placebo
Placebo given by subcutaneous injection once every 12 weeks (Q12W).
Olpasiran
Olpasiran given by subcutaneous injection Q12W.
Eligibility Criteria
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Inclusion Criteria
* Lp(a)≥ 200 nmol/L during screening
* History of ASCVD as evidenced by history of either:
* Myocardial infarction (presumed type 1 event due to plaque rupture/erosion) and/or
* Coronary revascularization with percutaneous coronary intervention AND at least 1 additional risk factor.
Exclusion Criteria
* Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) \> 3 x upper limit of normal (ULN), or total bilirubin (TBL) \> 2 x ULN during screening
* History of hemorrhagic stroke
* History of major bleeding disorder
* Planned cardiac surgery or arterial revascularization
* Severe heart failure
* Current, recent, or planned lipoprotein apheresis
* Previously received ribonucleic acid therapy specifically targeting Lp(a)
18 Years
85 Years
ALL
No
Sponsors
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Amgen
INDUSTRY
Responsible Party
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Principal Investigators
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MD
Role: STUDY_DIRECTOR
Amgen
Locations
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Ascension Saint Vincents Birmingham
Birmingham, Alabama, United States
Grandview Medical Center Affinity Cardiovascular Specialists, LLC
Birmingham, Alabama, United States
Heart Center Research LLC
Huntsville, Alabama, United States
Mobile Heart Specialists PC
Mobile, Alabama, United States
Alaska Cardiovascular Research Foundation
Anchorage, Alaska, United States
Elite Clinical Studies LLC
Phoenix, Arizona, United States
HonorHealth Research and Innovation Institute
Scottsdale, Arizona, United States
National Heart Institute
Beverly Hills, California, United States
Vitality Clinical Research
Beverly Hills, California, United States
University of California San Diego
La Jolla, California, United States
VA Greater Los Angeles Healthcare System
Los Angeles, California, United States
University of California Irvine
Orange, California, United States
University of California Los Angeles
Santa Monica, California, United States
Manshadi Heart Institute
Stockton, California, United States
Med Partners, Inc dba Premiere Medical Center, Inc
Toluca Lake, California, United States
UCHealth Memorial Central
Colorado Springs, Colorado, United States
Cardiology Associates of Fairfield County PC
Stamford, Connecticut, United States
MedStar Clinical Research
Washington D.C., District of Columbia, United States
Excel Medical Clinical Trials
Boca Raton, Florida, United States
Bay Area Cardiology
Brandon, Florida, United States
Clearwater Cardiovascular Consultants
Clearwater, Florida, United States
Cardiology Associates Research LLC
Daytona Beach, Florida, United States
Jellinger and Lerman MD PA dba The Center for Diabetes and Endocrine Care
Fort Lauderdale, Florida, United States
Elite Cardiac Research Center LLC
Hialeah, Florida, United States
East Coast Institute for Research, LLC
Jacksonville, Florida, United States
Westside Center for Clinical Research
Jacksonville, Florida, United States
University of Florida
Jacksonville, Florida, United States
East Coast Institute for Research LLC
Jacksonville, Florida, United States
Jacksonville Center for Clinical Research
Jacksonville, Florida, United States
Advanced Research for Health Improvement, LLC
Naples, Florida, United States
Ocala Cardiovascular Research
Ocala, Florida, United States
AdventHealth Medical Group Cardiology at Orlando
Orlando, Florida, United States
East Coast Institute for Research, LLC
Saint Augustine, Florida, United States
Saint Johns Center for Clinical Research
Saint Augustine, Florida, United States
Cardiovascular Center of Sarasota
Sarasota, Florida, United States
Care Access - Tampa
Tampa, Florida, United States
Piedmont Healthcare
Atlanta, Georgia, United States
Morehouse School of Medicine
Atlanta, Georgia, United States
Northeast Georgia Medical Center Wisteria Building
Cumming, Georgia, United States
NSC Research
Johns Creek, Georgia, United States
St Lukes Idaho Cardiology Associates
Meridian, Idaho, United States
Northwest Heart Clinical Research LLC
Arlington Heights, Illinois, United States
Northshore University Health System
Evanston, Illinois, United States
Advocate Lutheran General Hospital
Park Ridge, Illinois, United States
Cardiovascular Research of Northwest Indiana LLC
Munster, Indiana, United States
Reid Physician Associates
Richmond, Indiana, United States
MercyOne Iowa Heart Center
West Des Moines, Iowa, United States
University of Kansas Medical Center
Kansas City, Kansas, United States
Midwest Heart and Vascular Specialists
Overland Park, Kansas, United States
Saint Elizabeth Covington
Covington, Kentucky, United States
The Research Group of Lexington LLC
Lexington, Kentucky, United States
University of Louisville Health - Jewish Hospital
Louisville, Kentucky, United States
Louisiana Heart Center
Hammond, Louisiana, United States
Care Access - Lake Charles
Lake Charles, Louisiana, United States
Clinical Trials of America Inc
Monroe, Louisiana, United States
Monroe Research LLC
West Monroe, Louisiana, United States
Northern Light Eastern Maine Medical Center
Bangor, Maine, United States
University of Maryland Medical Center
Baltimore, Maryland, United States
Maryland Cardiovascular Specialists
Baltimore, Maryland, United States
Johns Hopkins University School of Medicine
Baltimore, Maryland, United States
Metropolitan Cardiovascular Consultants LLC
Beltsville, Maryland, United States
TidalHealth Peninsula Regional, Inc
Salisbury, Maryland, United States
Brigham and Womens Hospital
Boston, Massachusetts, United States
Henry Ford Hospital
Detroit, Michigan, United States
Ascension Saint John Hospital
Detroit, Michigan, United States
Advanced Cardiology Associates
Grand Rapids, Michigan, United States
Healthy Heart Cardiology
Grand Rapids, Michigan, United States
Sparrow Clinical Research Institute
Lansing, Michigan, United States
Arcturus Healthcare, Public Limited Company, Troy Internal Medicine Research Division
Troy, Michigan, United States
Fairview Health Services
Maplewood, Minnesota, United States
Minneapolis Heart Institute Foundation
Minneapolis, Minnesota, United States
University of Minnesota
Minneapolis, Minnesota, United States
Mayo Clinic Rochester
Rochester, Minnesota, United States
Cardiology Associates Research LLC
Tupelo, Mississippi, United States
Saint Louis Heart and Vascular PC
St Louis, Missouri, United States
Bryan Heart
Lincoln, Nebraska, United States
Palm Research Center Inc
Las Vegas, Nevada, United States
Renown Institute for Heart and Vascular Health
Reno, Nevada, United States
Saint Michaels Medical Center
Newark, New Jersey, United States
Overlook Medical Center
Summit, New Jersey, United States
New York Presbyterian Medical Group Hudson Valley Cardiology
Cortlandt Manor, New York, United States
Elligo Health Research
Kew Gardens, New York, United States
WMCHealth Heart and Vascular Institute Kingston Division of Cardiology
Kingston, New York, United States
Northwell Health Physician Partners Cardiology at Manhasset
Manhasset, New York, United States
New York University Langone Health
New York, New York, United States
Northwell Health Lenox Hill Heart and Vascular
New York, New York, United States
Icahn School of Medicine at Mount Sinai Queens
New York, New York, United States
Icahn School of Medicine at Mount Sinai
New York, New York, United States
Northwell Health Physician Partners at Peconic
Riverhead, New York, United States
Stony Brook University Hospital
Stony Brook, New York, United States
Westchester Medical Center
Valhalla, New York, United States
NY Family Docs
Woodhaven, New York, United States
Asheville Cardiology Associates
Asheville, North Carolina, United States
Novant Health Heart and Vascular Institute
Charlotte, North Carolina, United States
Duke University
Durham, North Carolina, United States
Moses H Cone Memorial Hospital
Greensboro, North Carolina, United States
Lapis Clinical Research
Mooresville, North Carolina, United States
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States
Lillestol Research LLC
Fargo, North Dakota, United States
TriHealth Good Samaritan Hospital
Cincinnati, Ohio, United States
University Hospitals Cleveland Medical Center
Cleveland, Ohio, United States
The OhioHealth Research Institute
Columbus, Ohio, United States
Kettering Medical Center
Kettering, Ohio, United States
Rama Research LLC
Marion, Ohio, United States
Oregon Health and Science University
Portland, Oregon, United States
Capital Area Research LLC
Newport, Pennsylvania, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States
Montefiore Medical Center - Bronx
Philadelphia, Pennsylvania, United States
Allegheny General Hospital
Pittsburgh, Pennsylvania, United States
Medical University of South Carolina
Charleston, South Carolina, United States
Prisma Health Midlands Cardiology
Columbia, South Carolina, United States
Piedmont Research Partners
Fort Mill, South Carolina, United States
Monument Health Clinical Research
Rapid City, South Dakota, United States
Stern Cardiovascular Foundation Inc
Germantown, Tennessee, United States
Tennessee Center for Clinical Trials
Tullahoma, Tennessee, United States
Texas Diabetes and Endocrinology
Austin, Texas, United States
Baylor Scott and White Heart and Vascular Hospital-Dallas
Dallas, Texas, United States
Southwest Family Medicine Associates
Dallas, Texas, United States
David Turbay, MD
El Paso, Texas, United States
Care Access - Georgetown
Georgetown, Texas, United States
Baylor College of Medicine
Houston, Texas, United States
Texas Cardiology Associates of Houston
Kingwood, Texas, United States
Texas Institute of Cardiology
McKinney, Texas, United States
Permian Research Foundation
Odessa, Texas, United States
Northwest Houston Heart Center
Tomball, Texas, United States
Inova Heart and Vascular Institute
Fairfax, Virginia, United States
Virginia Heart
Falls Church, Virginia, United States
Virginia Heart - Loudoun
Leesburg, Virginia, United States
Carient Heart and Vascular
Manassas, Virginia, United States
Bon Secours Cardiology
Midlothian, Virginia, United States
Tidewater Physicians Multispecialty Group Clinical Research
Newport News, Virginia, United States
Winchester Cardiology and Vascular Medicine
Winchester, Virginia, United States
Pulse Heart Institute
Puyallup, Washington, United States
Instituto de Investigaciones Clinicas Bahia Blanca
Bahía Blanca, Buenos Aires, Argentina
Cedic Centro de Investigacion Clinica
CABA, Buenos Aires, Argentina
Ciprec Centro de Investigacion y Prevencion Cardiovascular
CABA, Buenos Aires, Argentina
Cinme - Centro de Investigaciones Metabolicas
CABA, Buenos Aires, Argentina
Consultorio Medico Dr Litvak Bruno
CABA, Buenos Aires, Argentina
Cemedic Centro de Especialidades Medicas
CABA, Buenos Aires, Argentina
Centro Medico Dra Laura Maffei Investigacion Clinica Aplicada
CABA, Buenos Aires, Argentina
Consultorios Medicos Dr Besada
CABA, Buenos Aires, Argentina
Fundacion Respirar - Consultorios Medicos Dr Doreski
CABA, Buenos Aires, Argentina
Glenny Corp SA
Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina
Fundacion Favaloro
Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina
Icba Instituto Cardiovascular de Buenos Aires
Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina
Hospital Italiano de Buenos Aires
Cuidad Autonoma de Buenos Aires, Buenos Aires, Argentina
Ciad - Consultorio Integral de Atencion al Diabetico
Morón, Buenos Aires, Argentina
Instituto de Investigaciones Clinicas Quilmes
Quilmes, Buenos Aires, Argentina
Instituto de Investigaciones Clinicas de San Nicolas
San Nicolás de los Arroyos, Buenos Aires, Argentina
Instituto de Investigaciones Clinicas Zarate
Zárate, Buenos Aires, Argentina
Clinica Privada del Prado
Córdoba, Córdoba Province, Argentina
Instituto Latinoamericano de Investigaciones Medicas Cidim-Ilaim
Córdoba, Córdoba Province, Argentina
Instituto de Investigaciones Clinicas de Cordoba
Córdoba, Córdoba Province, Argentina
Clinica Fusavim Privada SRL
Villa María, Córdoba Province, Argentina
Instituto de Investigaciones Clinicas Rosario
Rosario, Santa Fe Province, Argentina
Clinica Adventista Belgrano
Buenos Aires, , Argentina
Instituto Medico Damic
Córdoba, , Argentina
Centro de Investigaciones Clinicas del Litoral
Santa Fe, , Argentina
Canberra Hospital
Garran, Australian Capital Territory, Australia
Royal Prince Alfred Hospital
Camperdown, New South Wales, Australia
Concord Repatriation General Hospital
Concord, New South Wales, Australia
Liverpool Hospital
Liverpool, New South Wales, Australia
Holdsworth House Medical Practice
Sydney, New South Wales, Australia
Wollongong Hospital
Wollongong, New South Wales, Australia
Advara HeartCare Wesley
Auchenflower, Queensland, Australia
Advara HeartCare Bundaberg
Bundaberg, Queensland, Australia
Royal Brisbane and Womens Hospital
Herston, Queensland, Australia
Core Research Group Pty Ltd
Milton, Queensland, Australia
Dr Heart Pty Ltd
Woolloongabba, Queensland, Australia
Nightingale Research
Adelaide, South Australia, Australia
Flinders Medical Centre
Bedford Park, South Australia, Australia
Advara HeartCare Leabrook
Leabrook, South Australia, Australia
Royal Hobart Hospital
Hobart, Tasmania, Australia
Advara HeartCare Berwick
Berwick, Victoria, Australia
Victorian Heart Hospital
Clayton, Victoria, Australia
The Cardiologists Proprietary Limited
Epping, Victoria, Australia
Barwon Health Geelong Hospital
Geelong, Victoria, Australia
Advara HeartCare Ringwood
Ringwood, Victoria, Australia
Advara HeartCare Joondalup
Joondalup, Western Australia, Australia
Mount Hospital
Murdoch, Western Australia, Australia
Linear Clinical Research Limited
Nedlands, Western Australia, Australia
Landeskrankenhaus Feldkirch
Feldkirch, , Austria
Medizinische Universitaet Graz
Graz, , Austria
Klinikum Klagenfurt am Woerthersee
Klagenfurt, , Austria
Krankenhaus der Barmherzigen Brueder Linz
Linz, , Austria
Landeskrankenhaus Salzburg
Salzburg, , Austria
Universitaetsklinikum Sankt Poelten
Sankt Pölten, , Austria
Klinik Landstrasse
Vienna, , Austria
Universitaetsklinikum Allgemeines Krankenhaus Wien
Vienna, , Austria
Klinik Hietzing
Vienna, , Austria
Klinik Ottakring
Vienna, , Austria
Krankenhaus Nord - Klinik Floridsdorf
Vienna, , Austria
Algemeen Stedelijk Ziekenhuis Aalst
Aalst, , Belgium
Onze Lieve Vrouw Ziekenhuis - campus Aalst
Aalst, , Belgium
Ziekenhuisnetwerk Antwerpen site Cadix
Antwerp, , Belgium
Cliniques universitaires de Bruxelles Hopital Erasme
Brussels, , Belgium
Algemeen Ziekenhuis Sint Blasius
Dendermonde, , Belgium
Universitair Ziekenhuis Antwerpen
Edegem, , Belgium
Ziekenhuis Oost-Limburg - Campus Sint-Jan
Genk, , Belgium
Algemeen Ziekenhuis Sint Lucas
Ghent, , Belgium
Jessa Ziekenhuis - Campus Virga Jesse
Hasselt, , Belgium
Universitair Ziekenhuis Leuven - Campus Gasthuisberg
Leuven, , Belgium
Centre Hospitalier Regional de la Citadelle
Liège, , Belgium
Algemeen Ziekenhuis Sint-Maarten
Mechelen, , Belgium
Algemeen Ziekenhuis Turnhout
Turnhout, , Belgium
Hospital Universitario Walter Cantidio
Fortaleza, Ceará, Brazil
Centro de Pesquisas em Diabetes e Doencas Endocrino Metabolicas
Fortaleza, Ceará, Brazil
Centro do Diagnostico e Pesquisa da Osteoporose do Espirito Santo
Vitória, Espírito Santo, Brazil
Hospital Santa Izabel
Salvador, Estado de Bahia, Brazil
Hospital Ana Nery
Salvador, Estado de Bahia, Brazil
Instituto de Ensino e Pesquisa do Hospital da Bahia
Salvador, Estado de Bahia, Brazil
Associacao de Amparo a Saude Ensino e Pesquisa
Brasília, Federal District, Brazil
Hospital das Clinicas da Universidade Federal de Goias
Goiânia, Goiás, Brazil
Hospital Universitario Maria Aparecida Pedrossian
Campo Grande, Mato Grosso do Sul, Brazil
Eurolatino Pesquisas Medicas
Uberlândia, Minas Gerais, Brazil
Quanta Diagnostico por Imagem
Curitiba, Paraná, Brazil
Nucleo de Pesquisa Clinica
Curitiba, Paraná, Brazil
Procape
Recife, Pernambuco, Brazil
Hospital Agamenon Magalhaes
Recife, Pernambuco, Brazil
Instituto Atena de Pesquisa Clínica
Natal, Rio Grande do Norte, Brazil
Hospital Sao Francisco da Santa Casa de Misericordia de Porto Alegre
Porto Alegre, Rio Grande do Sul, Brazil
Centro de Pesquisa Clínica Associação Hospitalar Moinhos de Vento
Porto Alegre, Rio Grande do Sul, Brazil
Hospital das Clinicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, Brazil
Nucleo de Pesquisa Clinica do Rio Grande do Sul
Porto Alegre, Rio Grande do Sul, Brazil
Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul
Porto Alegre, Rio Grande do Sul, Brazil
Instituto de Cardiologia do Rio Grande do Sul
Porto Alegre, Rio Grande do Sul, Brazil
Imv Pesquisa Cardiologica
Porto Alegre, Rio Grande do Sul, Brazil
FZ Pesquisa e Servicos em Cardiologia LTDA
Porto Alegre, Rio Grande do Sul, Brazil
AngioCor Blumenau
Blumenau, Santa Catarina, Brazil
jmf Clinica do Coracao ltda
Aracaju, Sergipe, Brazil
Instituto de Pesquisa Clínica de Campinas
Campinas, São Paulo, Brazil
Loema Instituto de Pesquisa Clinica e Consultores Ltda
Campinas, São Paulo, Brazil
icm Instituto do Coração de Marilia
Marília, São Paulo, Brazil
Clinicor Clinica Cardiologica Ltda
Ribeirão Preto, São Paulo, Brazil
Hospital Das Clinicas da Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo
Ribeirão Preto, São Paulo, Brazil
Hospital de Base de Sao Jose do Rio Preto
São José do Rio Preto, São Paulo, Brazil
Instituto de Pesquisa em Endocrinologia Clinica IPEC
São Paulo, São Paulo, Brazil
Sociedade Beneficente de Senhoras Hospital Sirio Libanes
São Paulo, São Paulo, Brazil
Instituto Dante Pazzanese de Cardiologia
São Paulo, São Paulo, Brazil
Instituto do Coracao do Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo
São Paulo, São Paulo, Brazil
Integral Pesquisa e Ensino
Votuporanga, São Paulo, Brazil
IBPClin Instituto Brasil de Pesquisa Clinica
Rio de Janeiro, , Brazil
Fundacao Pro-Coracao
Rio de Janeiro, , Brazil
Centro Paulista de Investigacoes Clinicas Cepic
São Paulo, , Brazil
Multiprofile Hospital for Active Treatment Puls AD
Blagoevgrad, , Bulgaria
Multiprofile Hospital for Active Treatment - Haskovo AD
Haskovo, , Bulgaria
Medical Center Medconsult Pleven OOD
Pleven, , Bulgaria
Multiprofile Hospital for Active Treatment Heart and Brain EAD
Pleven, , Bulgaria
Medical Center Cardiomed 2020 EOOD
Sliven, , Bulgaria
Diagnostic-Consultative Center Ascendent OOD
Sofia, , Bulgaria
Multiprofile Hospital for Active Treatment National Hospital of Cardiology EAD
Sofia, , Bulgaria
Acibadem City Clinic University Multiprofile Hospital for Active Treatment EOOD
Sofia, , Bulgaria
University Multiprofile Hospital for Active Treatment Tsaritsa Yoanna - ISUL EAD
Sofia, , Bulgaria
Medical Center Kalimat EOOD
Sofia, , Bulgaria
Medical Centre Synexus Sofia EOOD
Sofia, , Bulgaria
Medical Center Orpheus OOD
Stara Zagora, , Bulgaria
Ambulatory for Individual Practice for Specialized Medical Care - Kardio EOOD
Varna, , Bulgaria
ARC Biosystems Incorporated
Vancouver, British Columbia, Canada
Victoria Heart Institute Foundation
Victoria, British Columbia, Canada
Discovery Clinical Services Ltd
Victoria, British Columbia, Canada
LMC Clinical Research Incorporated
Brampton, Ontario, Canada
Brampton Clinical Trials
Brampton, Ontario, Canada
Cambridge Cardiac Care Centre
Cambridge, Ontario, Canada
LMC Clinical Research Incorporated Thornhill
Concord, Ontario, Canada
Hamilton Health Sciences Hamilton General Hospital
Hamilton, Ontario, Canada
One Heart Care
Mississauga, Ontario, Canada
North York Diagnostic and Cardiac Centre
North York, Ontario, Canada
Oakville Cardiovascular Research
Oakville, Ontario, Canada
Womens College Hospital
Toronto, Ontario, Canada
CPS Research
Waterloo, Ontario, Canada
Ecogene-21 Research
Chicoutimi, Quebec, Canada
Institut de recherches cliniques de Montreal
Montreal, Quebec, Canada
Research Institute of McGill University Health Center - Glen Site
Montreal, Quebec, Canada
Centre Hospitalier Universitaire de Quebec, Centre Hotel-Dieu de Quebec
Québec, Quebec, Canada
Institut Universitaire de cardiologie et de pneumologie de Quebec
Québec, Quebec, Canada
Clinique des Maladies Lipidiques de Quebec Incorporated
Québec, Quebec, Canada
Centre de sante et de services sociaux du Nord de Lanaudiere
Saint-Charles-Borromée, Quebec, Canada
Peking University Third Hospital
Beijing, Beijing Municipality, China
Beijing Hospital
Beijing, Beijing Municipality, China
The First Affiliated Hospital ,Sun-Yat Sen University
Guangzhou, Guangdong, China
Sun Yat-sen Memorial Hospital Sun Yat-sen University
Guangzhou, Guangdong, China
Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China
Guangdong Provincial Peoples Hospital
Guangzhou, Guangdong, China
Huizhou Central Peoples Hospital
Huizhou, Guangdong, China
The Peoples Hospital of Guangxi Zhuang Autonomous Region
Nanning, Guangxi, China
The Second Nanning Peoples Hospital
Nanning, Guangxi, China
Daqing Oilfield general Hospital
Daqing, Heilongjiang, China
The First Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, China
Nanyang Second General Hospital
Nanyang, Henan, China
The Second Xiangya Hospital of Central South University
Changsha, Hunan, China
The Third Xiangya Hospital of Central South University
Changsha, Hunan, China
Xiangtan Central Hospital
Xiangtan, Hunan, China
Nanjing First Hospital
Nanjing, Jiangsu, China
Nanjing Drum Tower Hospital
Nanjing, Jiangsu, China
Zhongda Hospital Southeast University
Nanjing, Jiangsu, China
The Second Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China
The First Affiliated Hospital of Soochow University
Suzhou, Jiangsu, China
Wuxi Peoples Hospital
Wuxi, Jiangsu, China
The Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, China
The Second Affiliated Hospital to Nanchang University
Nanchang, Jiangxi, China
Jilin Province Peoples Hospital
Changchun, Jilin, China
The First Hospital of Jilin University
Changchun, Jilin, China
China-Japan Union Hospital of Jilin University
Changchun, Jilin, China
The Peoples Hospital of Liaoning Province
Shenyang, Liaoning, China
General Hospital of Ningxia Medical University
Yinchuan, Ningxia, China
Shaanxi Provincial Peoples Hospital
Xi'an, Shaanxi, China
Jinan Central Hospital
Jinan, Shandong, China
West China Hospital of Sichuan University
Chengdu, Sichuan, China
Tianjin Medical University General Hospital
Tianjin, Tianjin Municipality, China
Tianjin Peoples Hospital
Tianjin, Tianjin Municipality, China
Tianjin Chest Hospital
Tianjin, Tianjin Municipality, China
The First Affiliated Hospital of Xinjiang Medical University
Ürümqi, Xinjiang, China
Zhejiang Provincial Peoples Hospital
Hangzhou, Zhejiang, China
The First Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, China
Beijing Friendship Hospital, Capital Medical University
Beijing, , China
Qingdao Fuwai Cardiovascular Hospital
Qingdao, , China
Shanghai General Hospital
Shanghai, , China
Shanghai Yangpu District Central Hospital（ Yangpu Hospital Affiliated to Tongji University）
Shanghai, , China
Renmin Hospital of Wuhan University
Wuhan, , China
Zhejiang Hospital
Zhejiang, , China
Jessenia as, Nemocnice Beroun
Beroun, , Czechia
Hornicka nemocnice s poliklinikou spol sro
Bílina, , Czechia
Medicus Services sro
Brandýs nad Labem, , Czechia
MTE Medical Center
Brno, , Czechia
Centrum pro zdravi sro
Brno, , Czechia
MUDr Karel Kameník sro
Brno, , Czechia
Kardiologicka ambulance Brno sro
Brno, , Czechia
Kardio Elbl sro
Brno, , Czechia
Ordinace pro choroby srdce sro
Chomutov, , Czechia
Nemocnice Ceske Budejovice as
České Budějovice, , Czechia
Dika centrum sro
Havirov - Mesto, , Czechia
Kardio Holesov sro
Holešov, , Czechia
MUDr Ladislava Harrerova, kardiologicka ordinace
Hradec Králové, , Czechia
Fakultni nemocnice Hradec Kralove
Hradec Králové, , Czechia
Nemocnice Jihlava po
Jihlava, , Czechia
Kardio Michal Cepelak sro
Klatovy IV, , Czechia
MUDr Zbynek Kosek, kardiologicka ambulance sro
Mladá Boleslav, , Czechia
Edumed sro
Náchod, , Czechia
PreventaMed sro
Olomouc, , Czechia
Fakultni nemocnice Ostrava
Ostrava, , Czechia
Mestska nemocnice Ostrava, po
Ostrava - Moravska Ostrava, , Czechia
Pedicor Trial sro
Ostrava-Dubina, , Czechia
Nemocnice Pardubickeho kraje as
Pardubice, , Czechia
Fakultni nemocnice Plzen
Pilsen, , Czechia
Policska nemocnice sro
Polička, , Czechia
Ordinace pro choroby srdce a cev
Prague, , Czechia
Vseobecna fakultni nemocnice v Praze
Prague, , Czechia
Institut klinicke a experimentalni mediciny
Prague, , Czechia
Milan Kvapil sro
Prague, , Czechia
Interni a kardiologicka ordinace
Prague, , Czechia
Endokrinologie Cerny Most sro
Prague, , Czechia
Kardiologicke centrum MUDr Janky Skrobakove sro
Praha 5 - Smichov, , Czechia
Poliklinika Ravak Pribram
Pribram VIII, , Czechia
Kardio Vaclavik sro, Interni a kardiologicka ambulance
Přerov, , Czechia
Kardiologicka ambulance MUDr Ferkl, sro
Trutnov, , Czechia
Clinical Trials Service sro
Uherské Hradiště, , Czechia
Cardio Research sro
Zlín, , Czechia
Krajska nemocnice T Bati as
Zlín, , Czechia
Aalborg Universitetshospital
Aalborg, , Denmark
Aarhus Universitetshospital
Aarhus N, , Denmark
Rigshospitalet
Copenhagen O, , Denmark
Sydvestjysk Sygehus
Esbjerg, , Denmark
Sanos Gandrup
Gandrup, , Denmark
Herlev Gentofte Hospital
Herlev, , Denmark
Sanos Clinic
Herlev, , Denmark
Regionshospitalet Gødstrup
Herning, , Denmark
Holbaek Sygehus
Holbæk, , Denmark
University of Fredriksberg Hospital
København NV, , Denmark
Amager Hospital
København S, , Denmark
Sjaellands Universitetshospital, Roskilde
Roskilde, , Denmark
Slagelse Sygehus
Slagelse, , Denmark
Svendborg Sygehus
Svendborg, , Denmark
Sanos Vejle
Vejle, , Denmark
Regionshospitalet Viborg
Viborg, , Denmark
Innomedica
Tallinn, , Estonia
Center for Clinical and Basic Research Tallinn
Tallinn, , Estonia
North Estonia Medical Centre Foundation
Tallinn, , Estonia
Tartu University Hospital
Tartu, , Estonia
Helsinki University Central Hospital
Helsinki, , Finland
Satucon Oy/Kuopion tyoterveys
Kuopio, , Finland
Oulu University Hospital
Oulu, , Finland
Tampere University Hospital
Tampere, , Finland
Suomen Terveystalo Oy
Turku, , Finland
Centre Hospitalier Regional Universitaire de Besancon, Hopital Jean Minjoz
Besançon, , France
Hospices Civils de Lyon Groupement Hospitalier Est, Hopital Louis Pradel
Bron, , France
Centre Hospitalier Régional Universitaire de Tours - Hôpital Trousseau
Chambray-lès-Tours, , France
Centre Hospitalier Compiegne-Noyon
Compiègne, , France
Centre Hospitalier Universitaire de Dijon - Hopital Francois Mitterrand
Dijon, , France
Centre Hospitalier Regional Universitaire de Lille - Hopital Claude Huriez
Lille, , France
Hopital de la Conception
Marseille, , France
Hopital Saint-Joseph
Marseille, , France
Centre Hospitalier Universitaire de Montpellier - Hopital Lapeyronie
Montpellier, , France
Centre Hospitalier Universitaire de Nantes - Hopital Guillaume et Rene Laennec
Nantes, , France
Centre Hospitalier Universitaire de Nice - Hopital Pasteur
Nice, , France
Hopital Saint Antoine
Paris, , France
Hopital Pitie-Salpetriere
Paris, , France
Hopital Bichat Claude Bernard
Paris, , France
Centre Hospitalier Universitaire de Reims - Hopital Robert Debre
Reims, , France
Centre Hospitalier Universitaire de Rennes - Hopital Pontchaillou
Rennes, , France
Centre Hospitalier Universitaire de Strasbourg - Hopital de Hautepierre
Strasbourg, , France
Centre Hospitalier Universitaire de Toulouse - Hopital Rangueil
Toulouse, , France
Polyclinique Vauban
Valenciennes, , France
Universitaetsklinikum Aachen
Aachen, , Germany
Universitaets-Herzzentrum Freiburg - Bad Krozingen
Bad Krozingen, , Germany
Universitaetsklinikum der Ruhr-Universitaet Bochum
Bad Oeynhausen, , Germany
Velocity Clinical Research GmbH
Berlin, , Germany
Charite - Universitaetsmedizin Berlin, Campus Benjamin Franklin
Berlin, , Germany
Charite - Universitaetsmedizin Berlin, Campus Virchow
Berlin, , Germany
Klinikum Links der Weser
Bremen, , Germany
Universitaetsklinikum Koeln
Cologne, , Germany
Universitaetsklinikum Dresden
Dresden, , Germany
Universitaetsklinikum Essen
Essen, , Germany
Universitaetsklinikum Frankfurt
Frankfurt am Main, , Germany
ClinPhenomics CVC GmbH
Frankfurt am Main, , Germany
Evangelisches Krankenhaus Goettingen-Weende
Göttingen, , Germany
Universitaetsmedizin Goettingen - Georg-August-Universitaet
Göttingen, , Germany
Universitaetsklinikum Hamburg-Eppendorf
Hamburg, , Germany
Cardiologicum Hamburg GbR
Hamburg, , Germany
Universitaetsklinikum Heidelberg
Heidelberg, , Germany
B Braun Ambulantes Herzzentrum Kassel mvz GmbH
Kassel, , Germany
Universitaetsklinikum Leipzig
Leipzig, , Germany
Otto von Guericke Universitaet Magdeburg
Magdeburg, , Germany
Universitaetsklinikum Mannheim
Mannheim, , Germany
Kardiologische Praxis Doktor Jens Taggeselle
Markkleeberg, , Germany
Klinikum rechts der Isar der TUM
München, , Germany
Universitaetsklinikum Muenster
Münster, , Germany
Kardiologische Gemeinschaftspraxis Papenburg
Papenburg, , Germany
Sana-Klinikum Remscheid GmbH
Remscheid, , Germany
Lipidambulanz der Universitaet Rostock
Rostock, , Germany
Klinik am See - Ruedersdorf
Rüdersdorf, , Germany
Hegau-Bodensee-Klinikum Singen
Singen, , Germany
Forschungszentrum Ruhr
Witten, , Germany
General Hospital of Athens Evaggelismos
Athens, , Greece
Athens Naval Hospital
Athens, , Greece
General Hospital of Athens Ippokrateio
Athens, , Greece
Laiko General Hospital
Athens, , Greece
Alexandra Hospital
Athens, , Greece
Attikon Hospital
Athens, , Greece
Konstantopoulio - Agia Olga Hospital of Nea Ionia
Athens, , Greece
Hygeia Hospital
Athens, , Greece
Metropolitan Hospital
Athens, , Greece
University Hospital of Heraklion
Heraklion, , Greece
University Hospital of Ioannina
Ioannina, , Greece
General Hospital of Mitilini Vostanio
Mytilene, , Greece
General Hospital of Thessaloniki Ahepa
Thessaloniki, , Greece
University of Hong Kong, Queen Mary Hospital
Hong Kong, , Hong Kong
Prince of Wales Hospital
Shatin, New Territories, , Hong Kong
Lausmed Kft
Baja, , Hungary
Dr Lakatos Ferenc Private Cardiology Practice
Békéscsaba, , Hungary
Budapesti Szent Ferenc Korhaz
Budapest, , Hungary
High Tech Medical Kft
Budapest, , Hungary
Clinexpert Kft
Budapest, , Hungary
Gottsegen Gyorgy Orszagos Kardiovaszkularis Intezet
Budapest, , Hungary
Semmelweis Egyetem Varosmajori Sziv es Ergyogyaszati Klinika
Budapest, , Hungary
Eszak-Pesti Centrum Korhaz - Honvedkorhaz
Budapest, , Hungary
Debreceni Egyetem Klinikai Kozpont
Debrecen, , Hungary
Pharma4 Trial Kft
Gyöngyös, , Hungary
BKS Research Kft
Hatvan, , Hungary
Selye Janos Korhaz
Komárom, , Hungary
Borsod-Abauj-Zemplen Varmegyei Kozponti Korhaz es Egyetemi Oktatokorhaz
Miskolc, , Hungary
Dr Nagy Laszlo Kardiologiai maganrendeles es SMO
Orosháza, , Hungary
Vita Verum Medical Bt
Székesfehérvár, , Hungary
Belvarosi Egeszseghaz Kft
Zalaegerszeg, , Hungary
Obudai Egeszsegugyi Centrum Kft
Zalaegerszeg, , Hungary
Hjartamidstodin
Kopavogur, , Iceland
Thjonustumidstod Rannsoknaverkefna
Kopavogur, , Iceland
Ospedali dell Ovest Vicentino
Arzignano, , Italy
IRCCS Azienda Ospedaliero Universitaria di Bologna Policlinico di Sant Orsola
Bologna, , Italy
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Brescia, , Italy
Azienda Ospedaliera Sant Anna e San Sebastiano
Caserta, , Italy
Azienda Ospedaliera Cannizzaro
Catania, , Italy
Azienda Ospedaliera Universitaria Renato Dulbecco
Catanzaro, , Italy
Azienda Ospedaliera Universitaria di Ferrara Arcispedale Sant Anna
Cona FE, , Italy
Azienda Ospedaliero Universitaria Careggi
Florence, , Italy
Ospedale Policlinico San Martino IRCCS
Genova, , Italy
IRCCS Centro Cardiologico Monzino
Milan, , Italy
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
Milan, , Italy
Azienda Ospedaliera Universitaria Federico II
Napoli, , Italy
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone
Palermo, , Italy
Ospedale degli Infermi di Rivoli
Rivoli, , Italy
Fondazione Policlinico Tor Vergata
Roma, , Italy
Azienda Ospedaliera Policlinico Umberto I
Roma, , Italy
IRCCS Istituto Clinico Humanitas
Rozzano MI, , Italy
Azienda Ospedaliera Universitaria Ospedale San Giovanni di Dio e Ruggi D Aragona
Salerno, , Italy
Multimedica
Sesto San Giovanni (MI), , Italy
Azienda Ospedaliera Ordine Mauriziano di Torino
Torino, , Italy
Kasugai Municipal Hospital
Kasugai-shi, Aichi-ken, Japan
Nagoya University Hospital
Nagoya, Aichi-ken, Japan
Tosei General Hospital
Seto-shi, Aichi-ken, Japan
Fujita Health University Hospital
Toyoake-shi, Aichi-ken, Japan
Hirosaki University Hospital
Hirosaki-shi, Aomori, Japan
Asahi General Hospital
Asahi-shi, Chiba, Japan
New Tokyo Heart Clinic
Matsudo-shi, Chiba, Japan
University of Fukui Hospital
Yoshida-gun, Fukui, Japan
Fukuoka University Hospital
Fukuoka, Fukuoka, Japan
Kokura Memorial Hospital
Kitakyushu-shi, Fukuoka, Japan
Japan Community Health care Organization Kyushu Hospital
Kitakyushu-shi, Fukuoka, Japan
Gifu Heart Center
Gifu, Gifu, Japan
Ogaki Municipal Hospital
Ogaki-shi, Gifu, Japan
Hiroshima City Hiroshima Citizens Hospital
Hiroshima, Hiroshima, Japan
Asahikawa City Hospital
Asahikawa-shi, Hokkaido, Japan
Hakodate Municipal Hospital
Hakodate-shi, Hokkaido, Japan
Tomakomai City Hospital
Tomakomai-shi, Hokkaido, Japan
Hyogo Prefectural Harima-Himeji General Medical Center
Himeji-shi, Hyōgo, Japan
Kobe City Medical Center General Hospital
Kobe, Hyōgo, Japan
Kanazawa Medical University Hospital
Kahoku-gun, Ishikawa-ken, Japan
Kanazawa University Hospital
Kanazawa, Ishikawa-ken, Japan
Iwate Prefectural Central Hospital
Morioka, Iwate, Japan
Takamatsu Red Cross Hospital
Takamatsu, Kagawa-ken, Japan
Kagawa Prefectural Central Hospital
Takamatsu, Kagawa-ken, Japan
Kagoshima City Hospital
Kagoshima, Kagoshima-ken, Japan
Tenyoukai Chuo Clinic
Kagoshima, Kagoshima-ken, Japan
Fujisawa City Hospital
Fujisawa-shi, Kanagawa, Japan
Tokai University Hospital
Isehara-shi, Kanagawa, Japan
Kitasato University Hospital
Sagamihara-shi, Kanagawa, Japan
Showa University Fujigaoka Hospital
Yokohama, Kanagawa, Japan
Yokohama City University Medical Center
Yokohama, Kanagawa, Japan
Yokohama Minami Kyousai Hospital
Yokohama, Kanagawa, Japan
Yokohama Sakae Kyosai Hospital Federation of National Public Service Personnel Mutual Association
Yokohama, Kanagawa, Japan
Chikamori Hospital
Kochi, Kochi, Japan
Kumamoto University Hospital
Kumamoto, Kumamoto, Japan
Saiseikai Kumamoto Hospital
Kumamoto, Kumamoto, Japan
Tohoku University Hospital
Sendai, Miyagi, Japan
Sendai Cardiovascular Center
Sendai, Miyagi, Japan
Miyazaki Medical Association Hospital
Miyazaki, Miyazaki, Japan
Shinshu University Hospital
Matsumoto-shi, Nagano, Japan
Niigata University Medical and Dental Hospital
Niigata, Niigata, Japan
Kawasaki Medical School Hospital
Kurashiki-shi, Okayama-ken, Japan
Rinku General Medical Center
Izumisano, Osaka, Japan
Sakurabashi Watanabe Advanced Healthcare Hospital
Osaka, Osaka, Japan
Osaka City General Hospital
Osaka, Osaka, Japan
Osaka Police Hospital
Osaka, Osaka, Japan
Osaka Metropolitan University Hospital
Osaka, Osaka, Japan
Osaka General Medical Center
Osaka, Osaka, Japan
Osaka University Hospital
Suita-shi, Osaka, Japan
Saga-ken Medical Centre Koseikan
Saga, Saga-ken, Japan
Ageo Central General Hospital
Ageo-shi, Saitama, Japan
Sanai Hospital
Saitama-shi, Saitama, Japan
National Hospital Organization Shizuoka Medical Center
Sunto-gun, Shizuoka, Japan
Juntendo University Hospital
Bunkyo-ku, Tokyo, Japan
Tokyo-Eki Center-building Clinic
Chuo-ku, Tokyo, Japan
Minamino Cardiovascular Hospital
Hachioji-shi, Tokyo, Japan
National Hospital Organization Tokyo Medical Center
Meguro-ku, Tokyo, Japan
Japanese Red Cross Musashino Hospital
Musashino-shi, Tokyo, Japan
Ome Medical Center
Ome-shi, Tokyo, Japan
Showa University Hospital
Shinagawa-ku, Tokyo, Japan
Tokyo Womens Medical University Hospital
Shinjuku-ku, Tokyo, Japan
Toyama Prefectural Central Hospital
Toyama, Toyama, Japan
Seiyu Memorial Hospital
Wakayama, Wakayama, Japan
Tokuyama Central Hospital
Shunan-shi, Yamaguchi, Japan
University of Yamanashi Hospital
Chuo-shi, Yamanashi, Japan
Klinikiniai sprendimai
Alytus, , Lithuania
Klinikiniai sprendimai
Kaunas, , Lithuania
Saules Seimos Medicinos Centras
Kaunas, , Lithuania
Kardiologijos ir reabilitacijos klinika
Klaipėda, , Lithuania
Pirmoji viltis JSC
Šiauliai, , Lithuania
Vilnius University Hospital Santaros Clinic Public Institution
Vilnius, , Lithuania
Virgen Cardiovascular Research SC
Guadalajara, Jalisco, Mexico
Eukarya PharmaSite
Monterrey, Nuevo León, Mexico
Centro para el Desarrollo de la Medicina y de Asistencia Medica Especializada SC
Culiacán, Sinaloa, Mexico
Consultorio de Medicina Especializada del Sector Privado
Xalapa, Veracruz, Mexico
Centro de investigacion Cardiometabolica
Aguascalientes, , Mexico
Fundacion Cardiovascular de Aguascalientes AC
Aguascalientes, , Mexico
Hospital Cardiologica Aguascalientes
Aguascalientes, , Mexico
Scientia Investigacion Clinica SC
Chihuahua City, , Mexico
Procliniq Investigacion Clinica
Mexico City, , Mexico
Meander Medisch Centrum
Amersfoort, , Netherlands
Onze Lieve Vrouwe Gasthuis
Amsterdam, , Netherlands
Academisch Medisch Centrum
Amsterdam, , Netherlands
Gelre Ziekenhuizen
Apeldoorn, , Netherlands
Rijnstate Ziekenhuis
Arnhem, , Netherlands
Bravis ziekenhuis, locatie Roosendaal
Bergen op Zoom, , Netherlands
Amphia ziekenhuis
Breda, , Netherlands
Reinier de Graaf Gasthuis
Delft, , Netherlands
Deventer Ziekenhuis
Deventer, , Netherlands
Catharina Ziekenhuis
Eindhoven, , Netherlands
Maxima Medisch Centrum
Eindhoven, , Netherlands
Medisch Spectrum Twente
Enschede, , Netherlands
Admiraal de Ruyter Ziekenhuis
Goes, , Netherlands
Groene Hart Ziekenhuis
Gouda, , Netherlands
Martini Ziekenhuis
Groningen, , Netherlands
Zuyderland Medisch Centrum
Heerlen, , Netherlands
Spaarne Gasthuis, locatie Haarlem Zuid
Hoofddorp, , Netherlands
Dijklander Ziekenhuis Hoorn
Hoorn, , Netherlands
Leids Universitair Medisch Centrum
Leiden, , Netherlands
Alrijne Ziekenhuis
Leiderdorp, , Netherlands
Radboud Universitair Medisch Centrum
Nijmegen, , Netherlands
Erasmus Medisch Centrum
Rotterdam, , Netherlands
D and A Research and Genetics
Sneek, , Netherlands
Haaglanden MC
The Hague, , Netherlands
Haga Ziekenhuis
The Hague, , Netherlands
Ziekenhuis Rivierenland
Tiel, , Netherlands
Elisabeth-TweeSteden Ziekenhuis
Tilburg, , Netherlands
Universitair Medisch Centrum Utrecht
Utrecht, , Netherlands
VieCuri Medisch Centrum
Venlo, , Netherlands
Oslo Universitetssykehus HF Aker sykehus
Oslo, , Norway
Oslo Universitetssykehus HF, Aker sykehus
Oslo, , Norway
Skedsmo Medisinske senter
Skedsmokorset, , Norway
American Heart of Poland Spolka Akcyjna
Bełchatów, , Poland
American Heart of Poland Spolka Akcyjna Polsko-Amerykanskie Kliniki Serca
Bielsko-Biala, , Poland
American Heart of Poland Spolka Akcyjna
Chrzanów, , Poland
American Heart of Poland Spolka Akcyjna Polsko-Amerykanskie Kliniki Serca
Dąbrowa Górnicza, , Poland
Uniwersyteckie Centrum Kliniczne
Gdansk, , Poland
NZOZ Medica Jerzy Cygler
Giżycko, , Poland
American Heart of Poland Spolka Akcyjna Polsko-Amerykanskie Kliniki Serca
Kędzierzyn-Koźle, , Poland
Jaroslaw Ciosek Rajtar-Medica Centrum Medyczne
Krakow, , Poland
Wojewodzki Specjalistyczny Szpital im dr Wladyslawa Bieganskiego w Lodzi
Lodz, , Poland
Miedziowe Centrum Zdrowia SA
Lubin, , Poland
CenterMed Spzoo Centermed Lublin
Lublin, , Poland
Clinical Best Solutions Sp zoo Spolka Komandytowa Gabinet Lekarski
Lublin, , Poland
NZOZ Twoja Przychodnia Spzoo Twoja Przychodnia Spzoo
Lublin, , Poland
Uniwersyteckie Centrum Stomatologii I Medycyny Specjalistycznej Spolka z ograniczona odpowiedzialnos
Poznan, , Poland
KO-MED Centra Kliniczne Sp zoo KO-MED Centra Kliniczne Pulawy
Puławy, , Poland
American Heart of Poland Spolka Akcyjna Polsko-Amerykanskie Kliniki Serca
Sztum, , Poland
American Heart of Poland Spolka Akcyjna Polsko-Amerykanskie Kliniki Serca
Tychy, , Poland
FutureMeds Warszawa Centrum
Warsaw, , Poland
Szpital Grochowski imienia Doktora medycyny Rafala Masztaka Spzoo
Warsaw, , Poland
Narodowy Instytut Kardiologii Stefana kardynala Wyszynskiego - Panstwowy Instytut Badawczy
Warsaw, , Poland
Futuremeds spolka z ograniczona odpowiedzialnoscia
Wroclaw, , Poland
Slaskie Centrum Chorob Serca w Zabrzu
Zabrze, , Poland
KO-MED Centra Kliniczne Zamosc
Zamość, , Poland
American Heart of Poland Spolka Akcyjna
Zgierz, , Poland
Unidade de Saude Local de Almada-Seixal, EPE - Hospital Garcia de Orta
Almada, , Portugal
Unidade Local de Saude de Amadora-Sintra, EPE
Amadora, , Portugal
Unidade Local de Saude da Regiao de Aveiro, EPE - Hospital Infante Dom Pedro
Aveiro, , Portugal
Unidade Local de Saude de Braga, EPE
Braga, , Portugal
Unidade Local de Saude de Lisboa Ocidental, EPE - Hospital de Santa Cruz
Carnaxide, , Portugal
Hospital de Cascais
Cascais, , Portugal
Unidade Local de Saude de Coimbra, EPE
Coimbra, , Portugal
Unidade Local de Saude do Alto Ave, EPE
Guimarães, , Portugal
Unidade Local de Saude de Matosinhos, EPE - Hospital Pedro Hispano
Matosinhos Municipality, , Portugal
Unidade Local de Saude de Santo Antonio, EPE - Hospital de Santo Antonio
Porto, , Portugal
Unidade Local de Saude de Entre Douro e Vouga, EPE - Hospital de Sao Sebastiao
Santa Maria da Feira, , Portugal
Unidade Local de Saude da Arrabida, EPE - Hospital de Sao Bernardo
Setúbal, , Portugal
Unidade Local de Saude de Gaia-Espinho, EPE
Vila Nova de Gaia, , Portugal
cmi Cardiologie - Dr Mercea Corina Delia
Baia Mare, , Romania
Spitalul Clinic Universitar de Urgenta Elias
Bucharest, , Romania
Spitalul Universitar de Urgenta Bucuresti
Bucharest, , Romania
Matcord Biomedica Buzau
Buzău, , Romania
SC Sal Med SRL
Piteşti, , Romania
Cardio Med Medical Center Targu Mures
Târgu Mureş, , Romania
Spitalul Clinic Judetean de Urgenta Targu Mures
Târgu Mureş, , Romania
Spitalul Clinic Municipal de Urgenta Timisoara
Timișoara, , Romania
Alian, sro
Bardejov, , Slovakia
Narodny ustav srdcovych a cievnych chorob, as
Bratislava, , Slovakia
Kardiovita sro
Bratislava, , Slovakia
Nemocnica s poliklinikou Brezno, no
Brezno, , Slovakia
Intergal, sro
Kláštor pod Znievom, , Slovakia
Medical group Kosice sro
Košice, , Slovakia
Zarmed, sro
Košice, , Slovakia
Cardio D and R, sro Kosice
Košice, , Slovakia
Kardio 1 sro
Lučenec, , Slovakia
Medi M and M sro
Moldava nad Bodvou, , Slovakia
Oralek, sro
Námestovo, , Slovakia
Kardiocentrum Nitra sro
Nitra, , Slovakia
Kardiomed NZ, sro
Nové Zámky, , Slovakia
Medikard, sro
Prešov, , Slovakia
Medispol, sro
Prešov, , Slovakia
Medilex sro
Rimavská Sobota, , Slovakia
Tatratrial sro
Rožňava, , Slovakia
Interna SK, sro
Svidník, , Slovakia
Areteus sro
Trebišov, , Slovakia
CardiOr, sro
Trenčín, , Slovakia
Dong-A University Hospital
Busan, , South Korea
Chonnam National University Hospital
Gwangju, , South Korea
Gachon University Gil Medical Center
Incheon, , South Korea
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, , South Korea
Korea University Anam Hospital
Seoul, , South Korea
Seoul National University Hospital
Seoul, , South Korea
Kangbuk Samsung Hospital
Seoul, , South Korea
Severance Hospital, Yonsei University Health System
Seoul, , South Korea
Asan Medical Center
Seoul, , South Korea
Samsung Medical Center
Seoul, , South Korea
The Catholic University of Korea Seoul St Marys Hospital
Seoul, , South Korea
Korea University Guro Hospital
Seoul, , South Korea
Ulsan University Hospital
Ulsan, , South Korea
Yonsei University Wonju Severance Christian Hospital
Wonju-si, Gangwon-do, , South Korea
Hospital Universitario Reina Sofia
Córdoba, Andalusia, Spain
Hospital Clinico Universitario Virgen de la Victoria
Málaga, Andalusia, Spain
Hospital Universitario Virgen Macarena
Seville, Andalusia, Spain
Hospital Universitario Virgen del Rocio
Seville, Andalusia, Spain
Hospital Universitario Miguel Servet
Zaragoza, Aragon, Spain
Hospital Universitario de Leon
León, Castille and León, Spain
Hospital Universitari Germans Trias i Pujol
Badalona, Catalonia, Spain
Hospital del Mar
Barcelona, Catalonia, Spain
Hospital de la Santa Creu i Sant Pau
Barcelona, Catalonia, Spain
Hospital Universitari Vall d Hebron
Barcelona, Catalonia, Spain
Hospital Clinic i Provincial de Barcelona
Barcelona, Catalonia, Spain
Hospital Universitari de Bellvitge
L'Hospitalet de Llobregat, Catalonia, Spain
Hospital de Sant Joan Despi Moises Broggi
Sant Joan Despí, Catalonia, Spain
Complexo Hospitalario Universitario A Coruña
A Coruña, Galicia, Spain
Hospital Alvaro Cunqueiro
Vigo, Galicia, Spain
Hospital Universitario Virgen de la Arrixaca
El Palmar, Murcia, Spain
Hospital de Cabueñes
Gijón, Principality of Asturias, Spain
Hospital Clinico Universitario de Valencia
Valencia, Valencia, Spain
Hospital Arnau de Vilanova de Valencia
Valencia, Valencia, Spain
Hospital Universitario Ramon y Cajal
Madrid, , Spain
Hospital Clinico San Carlos
Madrid, , Spain
Hospital Universitario 12 de Octubre
Madrid, , Spain
Falu Lasarett
Falun, , Sweden
Sahlgrenska Universitetssjukhuset
Gothenburg, , Sweden
Helsingborgs Lasarett
Helsingborg, , Sweden
Clemenstorgets Hjartmottagning
Lund, , Sweden
PharmaSite Malmo
Malmo, , Sweden
Karolinska Universitetssjukhuset Huddinge
Stockholm, , Sweden
Karolinska Universitetssjukhuset Solna
Stockholm, , Sweden
Hualien Tzu Chi Hospital
Hualien City, Hualien, Taiwan
Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, , Taiwan
Mackay Memorial Hospital Tamsui Branch
New Taipei City, , Taiwan
Chung Shan Medical University Hospital
Taichung, , Taiwan
Veterans General Hospital - Taichung
Taichung, , Taiwan
National Cheng Kung University Hospital
Tainan City, , Taiwan
National Taiwan University Hospital
Taipei, , Taiwan
Shin Kong Wu Ho-Su Memorial Hospital
Taipei, , Taiwan
Linkou Chang Gung Memorial Hospital of Chang Gung Medical Foundation
Taoyuan District, , Taiwan
Ormeau Clinical Trials Ltd
Belfast, , United Kingdom
Russell Hall Hospital
Birmingham, , United Kingdom
NIHR Patient Recruitment Centre Blackpool
Blackpool, , United Kingdom
NIHR Patient Recruitment Centre Bradford
Bradford, , United Kingdom
West Walk Surgery
Bristol, , United Kingdom
St Richards Hospital
Chichester, , United Kingdom
Rowden Surgery
Chippenham, , United Kingdom
Craigavon Area Hospital
Craigavon, , United Kingdom
Panthera Biopartners - London
Enfield, , United Kingdom
NIHR Patient Recruitment Centre Exeter
Exeter, , United Kingdom
Panthera Biopartners - Glasgow
Glasgow, , United Kingdom
Harefield Hospital
Harefield, , United Kingdom
Wycombe General Hospital
High Wycombe, , United Kingdom
Highlands Clinical Research Facility, Raigmore Hospital
Inverness, , United Kingdom
NIHR Patient Recruitment Centre Leicester
Leicester, , United Kingdom
Lincoln County Hospital
Lincoln, , United Kingdom
Queen Mary University of London
London, , United Kingdom
Hammersmith Hospital
London, , United Kingdom
University Hospital Llandough
Penarth, , United Kingdom
The Adam Practice
Poole, , United Kingdom
Panthera Biopartners - Preston
Preston, , United Kingdom
Lister Hospital
Stevenage, , United Kingdom
Countries
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References
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Nicholls SJ, Nelson AJ, Michael LF. Oral agents for lowering lipoprotein(a). Curr Opin Lipidol. 2024 Dec 1;35(6):275-280. doi: 10.1097/MOL.0000000000000953. Epub 2024 Sep 25.
Dimitriadis K, Theofilis P, Iliakis P, Pyrpyris N, Dri E, Sakalidis A, Soulaidopoulos S, Tsioufis P, Fragkoulis C, Chrysohoou C, Tsiachris D, Tsioufis K. Management of dyslipidemia in coronary artery disease: the present and the future. Coron Artery Dis. 2024 Sep 1;35(6):516-524. doi: 10.1097/MCA.0000000000001375. Epub 2024 Apr 29.
Karp A, Jacobs M, Barris B, Labkowsky A, Frishman WH. Lipoprotein(a): A Review of Risk Factors, Measurements, and Novel Treatment Modalities. Cardiol Rev. 2025 Jul-Aug 01;33(4):352-358. doi: 10.1097/CRD.0000000000000667. Epub 2024 Feb 28.
Related Links
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AmgenTrials clinical trials website
Other Identifiers
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20180244
Identifier Type: -
Identifier Source: org_study_id
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