Ureteric Jet Doppler Waveforms in Patients With Spinal Cord Injury

NCT ID: NCT05568862

Last Updated: 2022-10-07

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 42 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-06-17
• Study Completion Date: 2022-09-30

Brief Summary

Urinary dysfunction is very common in individuals with spinal cord injury. The urine flowing from the collecting ducts to the renal calyx stretches the calyces. ANS controlled peristaltic contractions originate in the proximal renal pelvis and travel down the ureters, pushing urine from the renal pelvis towards the bladder. The urine bolus delivered from the kidneys through the peristaltic contraction of the ureter creates an image called ureteric jet. Using the Doppler analysis of ureteral jets, previous studies have examined the changes in the ureteric jet pattern in pathological conditions such as the diagnosis of normal ureteral physiology.

Detailed Description

This cross-sectional study was conducted at a tertiary rehabilitation center. Eighteen spinal cord injury patients who met the inclusion criteria and 24 healthy volunteers were included in the study. The appearance of üreteric jet form and bladder wall thicknesses were obtained by urinary Doppler ultrasound both in patient and control groups. Detrusor pressure and bladder volume were measured only in patient group during urodynamic assessment.

Conditions

Spinal Cord Injuries

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

spinal cord injury

patient with spinal cord injury

Doppler ultrasound, Urodynamic assessment.

Intervention Type: DIAGNOSTIC_TEST

The patients included in the study group were given 600 cc of water in the morning and the Doppler ultrasound was performed 30 minutes later

Urodynamic assessment.

Intervention Type: DIAGNOSTIC_TEST

A transurethral double lumen catheter was used to measure intravesical pressure in the urodynamic unit for the patients in the study group immediately after the use of the Doppler USG

no spinal cord injury

patient without spinal cord injury

Doppler ultrasound, Urodynamic assessment.

Intervention Type: DIAGNOSTIC_TEST

The patients included in the study group were given 600 cc of water in the morning and the Doppler ultrasound was performed 30 minutes later

Interventions

Doppler ultrasound, Urodynamic assessment.

The patients included in the study group were given 600 cc of water in the morning and the Doppler ultrasound was performed 30 minutes later

Intervention Type: DIAGNOSTIC_TEST

Urodynamic assessment.

A transurethral double lumen catheter was used to measure intravesical pressure in the urodynamic unit for the patients in the study group immediately after the use of the Doppler USG

Intervention Type: DIAGNOSTIC_TEST

Eligibility Criteria

Inclusion Criteria

• With signs of upper motor neuron lesion,
• Suprasacral spinal cord injury,
• Normal urinary ultrasound findings
• Planned urodynamics

• Normal urinary ultrasonography

Exclusion Criteria

• Neurological disease other than spinal cord injury
• Urinary tract infection
• Urinary obstruction
• History of urinary tract Stones
• Diabetes, hypertension
• History of urinary surgery,
• Sacral injury
• Second motor neuron lesions (such as cauda equina, or cauda conus)

The control group

• Neurological disease
• Urinary tract infection
• Urinary obstruction
• History of urinary tract Stones
• Diabetes, hypertension

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

OTHER

Sponsor Role: lead

Responsible Party

Yasin Demir

Associate Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

İlkay Karabay

Role: PRINCIPAL_INVESTIGATOR

Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

Locations

Gaziler PMR, Training and Research Hospital, Department of PMR

Ankara, Çankaya, Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

ik

Identifier Type: -

Identifier Source: org_study_id