Patient Reported Outcomes for Bladder Management Strategies in Spinal Cord Injury

NCT ID: NCT02616081

Last Updated: 2021-11-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

1479 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-01

Study Completion Date

2018-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The investigators goal is to create a better understanding of patient reported outcomes for bladder management strategies (clean intermittent catheterization (CIC), indwelling catheter (IDC) and bladder surgery.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Our study is a longitudinal observational study between bladder management strategies, comparing outcomes measured by patient reported questionnaires.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Neurogenic Bladder Spinal Cord Injuries Quality of Life Incontinence

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Urinary Bladder Neurogenic Quality of Life Spinal cord injury incontinence Bladder

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Clean Intermittent Catheterization

Participants performing intermittent catheterization of their bladder, having not had augmentation cystoplasty or creation of a catheterizable channel

Clean Intermittent Catheterization

Intervention Type OTHER

Clean intermittent self catheterization is a standard of care.

Indwelling Catheter

Participants utilizing an Foley catheter or a suprapubic tube (cystostomy)

Indwelling Catheter

Intervention Type OTHER

Indwelling catheterization is a standard of care.

Surgery

Undergoing any of the following surgeries: augmentation cystoplasty with or without a catheterizable channel, creation of catheterizable channel alone, urinary diversion (conduit or continent catheterizable pouch)

Surgery

Intervention Type OTHER

Bladder surgery is a standard of care.

Voiding

Participants with volitional control, voiding into diapers or a condom catheter via crede, valsalva, or spontaneous leakage

Voiding

Intervention Type OTHER

Voiding spontaneously is a standard of care.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Clean Intermittent Catheterization

Clean intermittent self catheterization is a standard of care.

Intervention Type OTHER

Indwelling Catheter

Indwelling catheterization is a standard of care.

Intervention Type OTHER

Surgery

Bladder surgery is a standard of care.

Intervention Type OTHER

Voiding

Voiding spontaneously is a standard of care.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Participants with acquired spinal cord injury
* Participants with neurogenic bladder
* Participants must be undergoing or starting at least one of the following bladder management treatments at the time of enrollment. a) Clean intermittent catheterization (CIC) b) Have an indwelling catheter (IDC) c) Spontaneous voiding, and d) Have undergone bladder surgery
* Age 18 or older
* Willingness and ability to comply with study engagement
* Able to provide consent

Exclusion Criteria

* Degenerative spinal cord issues, such as multiple sclerosis, neuromuscular dysfunction
* Congenital spinal cord issues, such as spina bifida, myelomeningocele, or cerebral palsy
* Participants that belong to a vulnerable population (pregnant, prisoners, mentally handicapped, etc)
* Participants less than 18 years of age
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Patient-Centered Outcomes Research Institute

OTHER

Sponsor Role collaborator

University of Minnesota

OTHER

Sponsor Role collaborator

University of Michigan

OTHER

Sponsor Role collaborator

University of Utah

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Jeremy Myers

Associate Professor - School of Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Jeremy O Myers, MD

Role: PRINCIPAL_INVESTIGATOR

University of Utah School of Medicine - Urology

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University of Michigan

Ann Arbor, Michigan, United States

Site Status

University of Minnesota

Minneapolis, Minnesota, United States

Site Status

University of Utah

Salt Lake City, Utah, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

References

Explore related publications, articles, or registry entries linked to this study.

Patel DP, Lenherr SM, Stoffel JT, Elliott SP, Welk B, Presson AP, Jha A, Rosenbluth J, Myers JB; Neurogenic Bladder Research Group. Study protocol: patient reported outcomes for bladder management strategies in spinal cord injury. BMC Urol. 2017 Oct 10;17(1):95. doi: 10.1186/s12894-017-0286-3.

Reference Type RESULT
PMID: 29017505 (View on PubMed)

Crescenze IM, Lenherr SM, Myers JB, Elliott SP, Welk B, O'Dell D, Stoffel JT. Self-Reported Urological Hospitalizations or Emergency Room Visits in a Contemporary Spinal Cord Injury Cohort. J Urol. 2021 Feb;205(2):477-482. doi: 10.1097/JU.0000000000001386. Epub 2020 Oct 9.

Reference Type DERIVED
PMID: 33035138 (View on PubMed)

Provided Documents

Download supplemental materials such as informed consent forms, study protocols, or participant manuals.

Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Related Links

Access external resources that provide additional context or updates about the study.

http://www.nbrg.org

Neurogenic Bladder Research Group

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

82971

Identifier Type: -

Identifier Source: org_study_id