UK Validation of the Automated "AcceXible" Speech Analysis Software

NCT ID: NCT05534958

Last Updated: 2022-09-10

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 248 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2022-08-01
• Study Completion Date: 2023-12-31

Brief Summary

Dementia, especially dementia caused by Alzheimer's disease, is considered one of the most severe health problems of our time. It is currently known that the disease begins many years before clinical symptoms appear. The sooner the patient is diagnosed, the sooner the patient will be in a position to prevent further deterioration.

A recent orientation is the analysis of language in relation to the description of images with a high and varied semantic and emotional content. It can be studied that changes in the description of an image check if these changes are associated with the evolution of a person with probable impairment both in memory and cognitive as well as emotional, psychiatric, behavioral and even in their interaction with environmental factors especially those associated with socialization and loneliness.

The present study has the objective of validating a digital method for detection and follow-up of patients with mild cognitive impairment (MCI) or dementia in a memory clinic setting.

Conditions

Mild Cognitive Impairment and Dementia

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Healthy

Accexible

Intervention Type: DEVICE

Speech Analysis

Mild Cognitive Impairment

Accexible

Intervention Type: DEVICE

Speech Analysis

Early Dementia

Accexible

Intervention Type: DEVICE

Speech Analysis

Interventions

Accexible

Speech Analysis

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• Adult patients 55+ years of age with suspected MCI or diagnosis of dementia referred into secondary care memory clinic by their General Practitioner.
• Have English as first language (able to speak and understand verbal messages).
• Patients must have agreed to participate in the study and have voluntarily signed the informed consent.

• Healthy older adults (55+ years of age), without a diagnosis neurological, or psychiatric disorders or any clinical evidence of cognitive decline.
• Have English as first language (able to speak and understand verbal messages).
• Controls must have agreed to participate in the study and have voluntarily signed the informed consent.

Exclusion Criteria

• To have received a diagnosis of a significant psychiatric disorder or other cognitive impairment not due to neurodegeneration.
• To have significant vision problems that would affect the ability to perceive visual stimuli.
• To have significant hearing problems that would affect the ability to understand verbal cues.
• To be unable to give informed consent to participate in the study.

• Objective evidence of significant cognitive decline in any one domain.
• Score of <88 on ACE-III cognitive testing.

• Minimum Eligible Age: 55 Years
• Maximum Eligible Age: 90 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Cornwall Partnership NHS Foundation Trust

NETWORK

Sponsor Role: collaborator

Accexible

INDUSTRY

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Cornwall Partnership NHS Foundation Trust

Cornwell, , United Kingdom

Site Status: RECRUITING

Countries

United Kingdom

Central Contacts

Carla Zaldua

Role: CONTACT

carla@accexible.com

+34 649 33 22 95

Facility Contacts

Dr Simon Vann

Role: primary

Other Identifiers

AcceXible-Healthy,MCI,Dementia

Identifier Type: -

Identifier Source: org_study_id