Agility Training on Physical Performance, Cognitive Function and Brain Activities in Elderly

NCT ID: NCT05531396

Last Updated: 2022-09-08

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 30 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-09-05
• Study Completion Date: 2023-06-30

Brief Summary

Agility comprised of cognitive and physical functions, which influences whole-body movement with change of speed and direction. Agility training is widely used in athletes, and recent studies have begun to apply it into the elderly. Agility training is multidimensional and highly functional, which makes it possible to provide more efficient training in limited time. In elderly, the decrement of cognitive function, muscle strength in the upper and lower limbs, the percentage of body fat, body flexibility and endurance caused by aging will make it difficult for the elderly to perform movements. Therefore, it is essential to explore whether agility training can achieve the improvement of the physical function and cognitive function in elderly, and to find the relationship between the two functions and brain activity. Method: This study will recruit 60 participants, and randomly allocate to control group and agility training. The training groups will have 8 weeks of training, 2 times a week, 45 minutes of training each time. Assessment will be performed before and after intervention in 1-week, and with 1-month follow-up. Assessment including agility ability, physical function, cognitive function, brain activity, and functional assessment scales.

Conditions

Elderly; Healthy

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Health Education

Group Type: ACTIVE_COMPARATOR

Health Education

Intervention Type: OTHER

Participants in the control group will receive health educational guidelines. Guideline contents include home-based exercise program, nutrition recommendations, and fall prevention education. The home-based exercise program will emphasize how to safely and properly perform stretching and whole-body exercises.

Agility Training Group

Group Type: EXPERIMENTAL

Agility Training

Intervention Type: OTHER

Participants will receive 60 minutes of exercise, twice a week, for a total of 8 weeks, and training will be conducted by a well-trained physical therapist. The intervention will comprise a 5-minute warm-up, 45 minutes of main exercise, and a 10-minute cool-down period, for a total of 60 minutes each session. During the warm-up and cool-down, participants will do static and dynamic whole-body stretching exercises.

Interventions

Agility Training

Participants will receive 60 minutes of exercise, twice a week, for a total of 8 weeks, and training will be conducted by a well-trained physical therapist. The intervention will comprise a 5-minute warm-up, 45 minutes of main exercise, and a 10-minute cool-down period, for a total of 60 minutes each session. During the warm-up and cool-down, participants will do static and dynamic whole-body stretching exercises.

Intervention Type: OTHER

Health Education

Participants in the control group will receive health educational guidelines. Guideline contents include home-based exercise program, nutrition recommendations, and fall prevention education. The home-based exercise program will emphasize how to safely and properly perform stretching and whole-body exercises.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

1. older than 65 years old

2. score of Mini-Mental State Examination (MMSE) ≥ 24

3. able to walk independently for more than 30 meters without assistive aids

4. able to follow orders

Exclusion Criteria

1. poorly controlled or unstable systematic disease

2. has a history of central nervous system disease

3. currently taking antidepressants, anti-anxiety, or other psychiatric drugs that may affect blood flow in the brain

4. has other medical conditions for which exercise is contraindicated; (5) subjects with achromatopsia.

• Minimum Eligible Age: 65 Years
• Maximum Eligible Age: 100 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

National Taiwan University Hospital

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Yan Ci Liu, PhD

Role: PRINCIPAL_INVESTIGATOR

National Taiwan University

Central Contacts

Yan Ci Liu, PhD

Role: CONTACT

yanciliu@ntu.edu.tw

+886233668135

Yi Ting Hung, BS

Role: CONTACT

r09428008@ntu.edu.tw

+886233668135

Other Identifiers

202205012RINC

Identifier Type: -

Identifier Source: org_study_id