Effect of Hypocalcemia on the Outcome of Elderly Major Trauma Patients With Trauma-induced Coagulopathy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

371 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-01-01

Study Completion Date

2023-09-01

Brief Summary

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Hypocalcaemia is an independent risk factor of TIC in elderly trauma patients. TIC combined with hypocalcemia had worse coagulation function and more serious acidosis.

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Detailed Description

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This 5-year retrospective, observational, single-center study was conducted at the Second Affiliated Hospital of Zhejiang University Medical School (SAHZU, China). Elderly patients with trauma were registered when they were admitted into intensive care unit affiliated to department of Emergency medicine (EICU) since January 2015 and September 2020.The purpose of this study is to elucidate the effect of hypocalcemia on TIC in elderly trauma patients through a single-center retrospective study, so as to further optimize the diagnosis and treatment strategies for TIC in elderly trauma patients.

Conditions

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Coagulopathy Trauma

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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trauma induced coagulopathy

patients with INR\>1.2

hypocalcemia

Intervention Type OTHER

hypocalcemia or normocalcemia

non-trauma induced coagulopathy

patients with INR≤1.2

No interventions assigned to this group

Interventions

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hypocalcemia

hypocalcemia or normocalcemia

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* age≥65 years old
* history of trauma

Exclusion Criteria

* previous anticoagulants or antiplatelet medication;
* Coagulopathy caused by previous underlying diseases;
* Blood products transfused before admission;
* Cardiac arrest on admission;
* Malignant tumor;
* Data incomplete

Minimum Eligible Age

65 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No